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https://www.researchgate.net/publication/45437242_Monolithic_Controlled_Delivery_Systems_Part_I_Basic_Characteristics_and_Mechanisms
Monolithic Controlled Delivery Systems: Part I. ... The second type is a monolithic system in which . ... Basic characteristics and mechanisms of monolithic drug delivery systems were recently ...
https://www.youtube.com/watch?v=UfChh_EBSVY
Jun 25, 2016 · Nanoscience and drug delivery -- small particles for big problems Taylor Mabe ... Novel Drug Delivery System by Dr Abdul Bari Mohd - Duration: 36:40. Dr Bari 15,536 views.Author: Haider Naqvi
https://link.springer.com/chapter/10.1007/978-1-4757-4175-9_18
Abstract. Controlled drug release from monolithic systems can be achieved by diffusion, swelling, or erosion. In diffusion-controlled systems the drug is dissolved or dispersed in a polymer matrix and allowed to diffuse from the monolith.Author: J. Heller
https://patents.google.com/patent/US20100068169A1/en
This invention relates to an improved monolithic drug delivery dosage form which releases a pharmaceutically active agent at a predetermined rate. The dosage form comprises a salted-out or crosslinked polymer and a pharmaceutically active agent. The salted-out or crosslinked polymer functions to polymerically entangle the pharmaceutically active agent but, progressively relax on contact with ...Author: Sibongile Ruth Sibambo, Viness Pillay, Yahya Essop Choonara
https://wjpr.net/admin/assets/article_issue/1425551899.pdf
Drug Delivery System include Push pull osmotic pump, Osmotic brusting osmotic pump, Liquid oral osmotic system, Sandwiched osmotic tablets, Delayed delivery osmotic device, Monolithic osmotic system and Controlled porosity osmotic pump. Osmotic drug delivery devices are composed of an osmotically active drug core, which is
https://journals.sagepub.com/doi/full/10.1177/2211068211428189
Jan 27, 2012 · The reservoir-based system is one of the most common controlled drug delivery systems to date. In these systems, a drug core is surrounded by a polymer film, and the drug release rate is controlled by the properties of the polymer (e.g., polymer composition and molecular weight), the thickness of the coating, and the physicochemical properties of the enclosed drug, such as solubility, …Author: Wan-Wan Yang, Erik Pierstorff
https://www.sciencedirect.com/science/article/pii/S0168365900002224
Jul 03, 2000 · The monolithic osmotic tablet system was simple to be prepared as exempting from push layer and simplifying in the orifice drilling compared with the push–pull osmotic tablet. The monolithic osmotic tablet system may be used in drug controlled delivery …Author: Longxiao Liu, Gilson Khang, John M. Rhee, Hai Bang Lee
https://www.researchgate.net/profile/Rumiana_Blagoeva/publication/45437242_Monolithic_Controlled_Delivery_Systems_Part_I_Basic_Characteristics_and_Mechanisms/links/02e7e5364b3421b8e8000000.pdf
Monolithic Controlled Delivery Systems: Part I. ... Controlled delivery, Drug release, Monolithic systems, Diffusion, ... The simplest way for preparing a monolithic system is to compress, in a ...
https://www.hansvanlaarhoven.nl/reservoir-system/
In a reservoir system the drug is either molecular dissolved or dispersed in a reservoir that is surrounded by a rate limiting inert membrane. In a monolithic or matrix device this membrane is absent. Although controlled delivery from a monolithic device is very well possible, the presence of a membrane normally provides for a better release ...
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