Mitochondria Targeted Drug Delivery

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Mitochondria-targeted drug delivery in neurodegenerative ...

    https://www.sciencedirect.com/science/article/pii/B9780128177761000055
    Nontargeted drug delivery through the systemic route spreads to the whole body and causes side-effects. To minimize these limitations of the systemic drug-delivery system, various methodologies like targeted drug delivery are adopted , . However, the targeted delivery of …Author: Saravana Babu Chidambaram, Bipul Ray, Abid Bhat, Arehally Marappa Mahalakshmi, Tuladhar Sunanda, Pad...

Targeted Drug Delivery to the Mitochondria SpringerLink

    https://link.springer.com/chapter/10.1007%2F978-3-319-11355-5_7
    Nov 05, 2014 · Yamada Y (2007) Mitochondrial drug delivery and mitochondrial disease therapy – an approach to liposome-based delivery targeted to mitochondria. …Author: Udita Agrawal, Rajeev Sharma, Suresh P. Vyas

Drug delivery to mitochondria: the key to mitochondrial ...

    https://www.sciencedirect.com/science/article/pii/S0169409X99000691
    Mitochondria are a promising intracellular target for drug delivery , because damage to this organelle contributes to a range of human disorders and because mitochondrial function is important in apoptosis, oxidative damage, calcium metabolism, diabetes and obesity .Author: Michael P Murphy, Robin A.J Smith

Design of a Functionalized Metal–Organic Framework System ...

    https://pubs.acs.org/doi/10.1021/jacs.0c00188
    Mitochondria play a key role in oncogenesis and constitute one of the most important targets for cancer treatments. Although the most effective way to deliver drugs to mitochondria is by covalently linking them to a lipophilic cation, the in vivo delivery of free drugs still constitutes a critical bottleneck. Herein, we report the design of a mitochondria-targeted metal–organic framework ...Author: Salame Haddad, Isabel Abanades Lazaro, Marcus Fantham, Ajay Mishra, Joaquin Silvestre-Albero, Johann...

Targeted Delivery of Doxorubicin to Mitochondria ACS ...

    https://pubs.acs.org/doi/abs/10.1021/cb400095v
    Recent Progress in Mitochondria-Targeted Drug and Drug-Free Agents for Cancer Therapy. Cancers 2020, 12 (1) , 4. DOI: 10.3390/cancers12010004. Lifo Ruan, Mengxue Zhou, Jun Chen, Hui Huang, Jiayu Zhang, Hongyan Sun, Zhifang Chai, Yi Hu. Thermoresponsive drug delivery to mitochondria in vivo.Author: Graham R. Chamberlain, David V. Tulumello, Shana O. Kelley

Targeted Drug Delivery to the Mitochondria - ResearchGate

    https://www.researchgate.net/publication/278681699_Targeted_Drug_Delivery_to_the_Mitochondria
    Request PDF Targeted Drug Delivery to the Mitochondria Mitochondria are of an increasing interest in pharmaceutical and medical research since it has emerged as an intriguing target for ...

Development of Drug Dual-Carriers Delivery System with ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970626
    Jan 16, 2020 · Purpose. Multifunctional drug delivery systems (DDS) are emerging as a new strategy to highly treat malignant tumors. The aim of this study is to develop a drug dual-carriers delivery system (DDDS) using the natural protein ferritin (FRT) and a nanoscale graphene oxide (NGO) as dual-carriers.Author: Xiaoxia Guo, Jie Mei, Chunping Zhang

Mitochondria-targeting particles - PubMed Central (PMC)

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294695/
    Targeted drug delivery systems not only facilitate drug delivery to the desired site of action, but often protect the active ingredient from degradation . Currently, mitochondria have become a promising therapeutic target for the prevention and treatment of various illnesses such as cancer, neurodegenerative diseases, ischemia-reperfusion ...Author: Amaraporn Wongrakpanich, Sean M Geary, Mei-ling A Joiner, Mark E Anderson, Aliasger K Salem

Mitochondria-targeted drug delivery system for cancer ...

    https://www.tandfonline.com/doi/abs/10.3109/1061186X.2015.1108325
    Aug 05, 2016 · Mitochondria-targeted drug delivery system for cancer treatment. Zhi-Peng Chen Department of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, P.R. China and , ...Author: Zhi-Peng Chen, Man Li, Liu-Jie Zhang, Jia-Yu He, Li Wu, Yan-Yu Xiao, Jin-Ao Duan, Ting Cai, Wei-Dong...

[Full text] Development of Drug Dual-Carriers Delivery ...

    https://www.dovepress.com/development-of-drug-dual-carriers-delivery-system-with-mitochondria-ta-peer-reviewed-fulltext-article-IJN
    Development of Drug Dual-Carriers Delivery System with Mitochondria-Targeted and pH/Heat Responsive Capacity for Synergistic Photothermal-Chemotherapy of Ovarian CancerAuthor: Xiaoxia Guo, Jie Mei, Chunping Zhang

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