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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716876/
These features address many shortcomings of current, widely used hydrogel systems for drug delivery. The results show that injectable cryogels can be formed with high retention of encapsulated Laponite. Porous cryogels were formed by partially freezing a prepolymer solution containing AlgN, AlgT, and Laponite nanoplatelets.Author: Sandeep T. Koshy, Sandeep T. Koshy, David K.Y. Zhang, David K.Y. Zhang, Joshua M. Grolman, Joshua M....
https://www.ncbi.nlm.nih.gov/pubmed/29128539
Injectable nanocomposite cryogels for versatile protein drug delivery. Koshy ST(1), Zhang DKY(2), Grolman JM(2), Stafford AG(3), Mooney DJ(4). Author information: (1)John A. Paulson School of Engineering and Applied Sciences, Harvard University, 29 Oxford Street, Cambridge, MA 02138, USA; Harvard-MIT Division of Health Sciences and Technology, 77 Massachusetts Avenue, Cambridge …Author: Sandeep T. Koshy, Sandeep T. Koshy, David K.Y. Zhang, David K.Y. Zhang, Joshua M. Grolman, Joshua M....
https://www.sciencedirect.com/science/article/pii/S1742706117307043
Injectable nanocomposite cryogels for versatile protein drug delivery Author links open overlay panel Sandeep T. Koshy a c David K.Y. Zhang a b Joshua M. Grolman a b Alexander G. Stafford b David J…Author: Sandeep T. Koshy, Sandeep T. Koshy, David K.Y. Zhang, David K.Y. Zhang, Joshua M. Grolman, Joshua M....
https://mooneylab.seas.harvard.edu/publications/injectable-nanocomposite-cryogels-versatile-protein-drug-delivery
Koshy ST, Zhang DKY, Grolman JM, Stafford AG, Mooney DJ. Injectable nanocomposite cryogels for versatile protein drug delivery.
https://www.cell.com/trends/biotechnology/fulltext/S0167-7799(19)30239-2
Unlike standard injectable cryogels that are typically covalently crosslinked, tough cryogels can be successfully injected through 18G needles. This type of cryogel exhibits high stretchability, in part due to reversible ionic crosslinking and self-healing properties.Author: Loek J. Eggermont, Zachary J. Rogers, Thibault Colombani, Adnan Memic, Sidi A. Bencherif
https://www.nature.com/articles/s41467-018-04998-9
Jul 17, 2018 · In this study, we developed injectable CNT-reinforced shape memory nanocomposite cryogel hemostatic dressings with robust mechanical strength, rapid blood-triggered shape recovery, high blood uptake capacity, and rapid blood absorption …Author: Xin Zhao, Baolin Guo, Hao Wu, Yongping Liang, Peter X. Ma
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050275/
In this study, we aim to develop injectable antibacterial and conductive nanocomposite cryogels based on CNT-reinforced glycidyl methacrylate (GMA) functionalized quaternized chitosan (QCSG) with robust mechanical property, rapid blood-triggered shape recovery, rapid blood absorption speed, excellent NIR stimuli-responsivity, and we further demonstrate their great potential for in vivo lethal …Author: Xin Zhao, Baolin Guo, Hao Wu, Yongping Liang, Peter X. Ma
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