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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891846/
Dec 28, 2013 · Even though these targeted miRNA therapeutic delivery systems showed enhanced activity in tissue culture and mouse models, they do not guarantee the same result in human beings. Like most targeted delivery systems, the accumulation of the particles is limited by the flow of particles into the diseased tissue,...Author: Yu Zhang, Zaijie Wang, Richard A. Gemeinhart
https://www.sciencedaily.com/releases/2018/11/181120151853.htm
Nov 20, 2018 · A method for large-scale production of extracellular vesicles enriched with specific microRNAs (miRNAs) has been developed in the Wake Forest Institute for Regenerative Medicine (WFIRM) labs, offering a manufacturing standardization process which may have therapeutic applications and clinical impact.
https://newsroom.wakehealth.edu/News-Releases/2018/11/A-Trojan-Horse-Delivery-Method-for-miRNA-enriched-Extracellular-Vesicles
Nov 19, 2018 · November 19, 2018. A method for large-scale production of extracellular vesicles enriched with specific microRNAs (miRNAs) has been developed in the Wake Forest Institute for Regenerative Medicine (WFIRM) labs, offering a manufacturing standardization process which may have therapeutic applications and clinical impact.
https://medicalxpress.com/news/2018-11-trojan-horse-delivery-method-mirna-enriched.html
Nov 20, 2018 · A Trojan horse delivery method for miRNA-enriched extracellular vesicles by Wake Forest University Baptist Medical Center MicroRNA and …
https://bioengineer.org/a-trojan-horse-delivery-method-for-mirna-enriched-extracellular-vesicles/
A method for large-scale production of extracellular vesicles enriched with specific microRNAs (miRNAs) has been developed in the Wake Forest Institute for Regenerative Medicine (WFIRM) labs, offering a manufacturing standardization process which may have therapeutic applications and clinical impact.
https://www.nextbigfuture.com/2015/12/new-delivery-method-for-microrna-cancer.html
Dec 29, 2015 · The therapeutic potential of miRNA (miR) in cancer is limited by the lack of efficient delivery vehicles. Here, we show that a self-assembled dual-color RNA-triple-helix structure comprising two miRNAs—a miR mimic (tumor suppressor miRNA) and an antagomiR (oncomiR inhibitor)—provides outstanding capability to synergistically abrogate tumors.
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