Microrna Delivery By Nanoparticles

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MicroRNA delivery through nanoparticles - ScienceDirect

    https://www.sciencedirect.com/science/article/pii/S0168365919305796
    MicroRNAs (miRNAs) are attracting a growing interest in the scientific community due to their central role in the etiology of major diseases. On the other hand, nanoparticle carriers offer unprecedented opportunities for cell specific controlled delivery of miRNAs for therapeutic purposes.Author: Sharon Wei Ling Lee, Camilla Paoletti, Marco Campisi, Tatsuya Osaki, Tatsuya Osaki, Giulia Adriani, ...

microRNA Delivery by Nanoparticles – miRNA Blog

    https://mirnablog.com/microrna-delivery-by-nanoparticles/
    Two groups have recently published results of microRNA delivery by nanoparticles. The first group, at University of California San Diego 1 , identified miR-132 as a highly upregulated miRNA in a human embryonic stem cell model of vasculogenesis and showed that the miRNA miR-132 acts as an angiogenic switch by targeting p120RasGAP in the endothelium and thereby inducing …

Nanotechnology based approaches for detection and delivery ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897953/
    Apr 13, 2018 · Like animals, the RNA nanoparticle based miRNA delivery technique can be utilised in plants to target those biotic and abiotic stresses against which there is no effective strategy for combating them. RNA nanotechnology may revolutionize the crop improvement programmes which will be a step towards food security worldwide.Author: Vrantika Chaudhary, Sumit Jangra, Neelam R. Yadav

Nanoparticle-Based Delivery of Tumor Suppressor microRNA ...

    https://www.mdpi.com/2073-4409/9/2/521/pdf
    with microRNA degradation, transient expression and poor targeting, novel nanoparticles are being developed and employed to shield microRNAs for tumor-targeted delivery. This review focuses on studies describing a variety of both natural and synthetic nanoparticle delivery vehicles that haveAuthor: Clodagh P. O’Neill, Róisín M. Dwyer

Lipid nanocarriers for microRNA delivery - ScienceDirect

    https://www.sciencedirect.com/science/article/pii/S0009308419300465
    MicroRNAs need effective delivery systems to avoid degradation and to allow targeted delivery with cytoplasmic release. Lipid nanocarriers present a versatile and flexible nanoparticle platform for the safe delivery of microRNA therapeutics.Author: Marcel Scheideler, Ivan Vidakovic, Ruth Prassl

Nanotechnology based approaches for detection and delivery ...

    https://jnanobiotechnology.biomedcentral.com/articles/10.1186/s12951-018-0368-8
    Apr 13, 2018 · RNA nanoparticles with many unique features are promising candidates in disease treatment. The miRNAs are involved in many biochemical and developmental pathways and their regulation in plants and animals. These appear to be a powerful tool for controlling various pathological diseases in human, plants and animals,...Author: Vrantika Chaudhary, Sumit Jangra, Neelam R. Yadav

Nanoparticle-based therapy in an in vivo microRNA-155 (miR ...

    https://www.pnas.org/content/109/26/E1695
    Jun 26, 2012 · We show that systemic delivery of antisense peptide nucleic acids encapsulated in unique polymer nanoparticles inhibits miR-155 and slows the growth of these “addicted” pre-B-cell tumors in vivo, suggesting a promising therapeutic option for lymphoma/leukemia.Author: Babar Ia, Cheng Cj, Booth Cj, Liang X, Weidhaas Jb, Saltzman Wm, Slack Fj

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