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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1167690/
Nanoparticles and microparticles for drug and vaccine delivery. J Kreuter Institut für Pharmazeutische Technologie, J.W. Goethe-Universität, Frankfurt/Main, Germany.Author: Kreuter J
https://www.tandfonline.com/doi/abs/10.1586/14760584.6.3.401
While many hurdles must be overcome before targeted mucosal vaccine delivery becomes a practical reality, this is a potential area of research that has important implications for future vaccine development. This review comprises various aspects that could be decisive in the development of polymer based mucosal vaccine delivery systems.
https://www.nature.com/articles/nm.2866
Jul 15, 2012 · Oral vaccine delivery seems preferable but runs the risk of the vaccine's destruction in the upper gastrointestinal tract. Therefore, we designed a large intestine–targeted oral delivery …
https://www.mdpi.com/2076-393X/4/4/45/htm
Synthetic biodegradable microparticle and nanoparticle platform technology provides the opportunity to design particles varying in composition, size, shape and surface properties for application in vaccine development. The use of particle vaccine formulations allows improvement of antigen stability and immunogenicity while allowing targeted delivery and slow release. This technology has been ...
https://pubs.rsc.org/en/content/articlelanding/2016/tb/c5tb01623a
The magnitude of the mucosal immune response was comparable to the gold-standard adjuvant cholera toxin B (CTB). Our results indicate that OVA-KFE8/CaCO 3 composite microparticles are efficient self-adjuvanting oral vaccine delivery vehicles for induction of mucosal antibody responses.
https://pubag.nal.usda.gov/catalog/6837599
Poly(diaminosulfide) Microparticle-Based Vaccine for Delivery of Leptospiral Antigens Author: Wafa, Emad I., Wilson ... it can be concluded that L203-PNSN is a novel first-in-class microparticle-based Leptospira vaccine that represents a powerful platform with the potential to serve as a prophylactic vaccine against leptospiral infection in ...
https://ir.uiowa.edu/etd/2922/
Recommended Citation. Krishnamachari, Yogita. "PLGA microparticle based vaccine carriers for an improved and efficacious tumor therapy." PhD (Doctor of Philosophy) thesis, University of Iowa, 2011.
https://www.researchgate.net/publication/330285130_Coordination_microparticle_vaccine_engineered_from_tumor_cell_templates
A number of recent studies using polymeric microparticle delivery of TL, with or without adjuvants, have produced promising results in preclinical studies. ... The choice of CpG-ODN class as ...
https://www.nature.com/articles/srep13155
Aug 17, 2015 · Targeted delivery of self-antigens to the immune system in a mode that stimulates a tolerance-inducing pathway has proven difficult. To address this hurdle, we developed a vaccine …
https://cdr.lib.unc.edu/concern/dissertations/8910jv27b
Aerosol Delivery of Recombinant Antigen 85B in Microparticle Vaccine Systems for Protection Against Tuberculosis
https://www.researchgate.net/publication/11767617_Microparticle_vaccine_approaches_to_stimulate_mucosal_immunisation
Request PDF Microparticle vaccine approaches to stimulate mucosal immunisation Entrapment of antigens in biodegradable particles for mucosal immunisation has given successful outcomes in ...
https://digitalcommons.utep.edu/open_etd/2604/
It is hypothesized that the use of a DNA delivery system incorporating copper or zinc metallo-lipid microparticles will increase the immunogenicity of the DNA leishmaniasis vaccine candidate by decreasing the amount of degradation that occurs prior to the delivery to the target cells. Methodology.
http://www.eurekaselect.com/108715
Keywords:Antigen, controlled release, immunity, malaria, midgut, mosquito, nanotechnology, natural boosting, sexual stages, transmission-blocking vaccine. Abstract:Malaria sexual stage and mosquito transmission-blocking vaccines (SSM-TBV) have recently gained prominence as a necessary tool for malaria eradication. SSM-TBVs are unique in that ...
https://www.ondrugdelivery.com/enabling-subcutaneous-delivery-of-biologics/
Elektrofi has developed a next-generation microparticle-based suspension formulation, Elektroject™, which directly addresses the current challenges of SC mAb delivery by enabling ultra-high concentrations (>400 mg/mL) of protein, while maintaining a …
http://dspace.mit.edu/handle/1721.1/97484
Antigen Delivery by Lipid-Enveloped PLGA Microparticle Vaccines Mediated by in Situ Vesicle Shedding ... suggesting that in situ release of antigen-loaded vesicles plays a key role in the remarkable potency of LCMPs as vaccine adjuvants. ... Anna Bershteyn, Monica P. Crespo, and Darrell J. Irvine. “Antigen Delivery by Lipid-Enveloped PLGA ...
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