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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465014/
Purpose. To design and develop a drug-delivery system containing a combination of poly(d, l-lactide-co-glycolide) (PLGA) microparticles and alginate hydrogel for sustained release of retinoids to treat retinal blinding diseases that result from an inadequate supply of retinol and generation of 11-cis-retinal.Author: Song Qi Gao, Tadao Maeda, Kiichiro Okano, Krzysztof Palczewski
http://www.ijpbs.com/ijpbsadmin/upload/ijpbs_518f888512e54.pdf
A well designed controlled drug delivery system can overcome some of the problems of conventional drug delivery system and enhance the therapeutic efficacy of a given drug. To obtain maximum therapeutic efficacy, it becomes necessary to deliver the agent to the target tissue in the optimal amount in the right period of time there by
https://link.springer.com/chapter/10.1007%2F3-540-32702-9_3
Microparticles offer various significant advantages as drug delivery systems, including: (i) an effective protection of the encapsulated active agent against (e.g. enzymatic) degradation, (ii) the possibility to accurately control the release rate of the incorporated drug over periods of hours to months, and (iii) an easy administration ...Author: Juergen Siepmann, Florence Siepmann
https://www.sciencedirect.com/science/article/pii/S131901641400111X
4. Role of microparticulate carrier for targeted drug delivery to colon for ulcerative colitis. Polymeric microparticles have turned out to be a promising approach as a targeted drug delivery system for the treatment of ulcerative colitis.Author: Nidhi, Muzamil Rashid, Veerpal Kaur, Supandeep Singh Hallan, Saurabh Sharma, Neeraj Mishra
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093624/
Microparticulate drug delivery systems are an interesting and promising option when developing an oral controlled release system. The objective of this paper is to take a closer look at microparticles as drug delivery devices for increasing efficiency of drug delivery, improving the release profile and drug targeting.
https://lubrizolcdmo.com/presentations/microparticles-as-controlled-release-drug-delivery-systems-presentation/
Oct 30, 2019 · LLS Health CDMO - Microparticles as Controlled Release Drug Delivery Systems Presentation from LLS Health, The leading CDMO experts.
http://sphinxsai.com/Vol.3No.3/pharm/pdf/PT=05(1242-1254)JS11.pdf
system. Targeting of drug to the particular site is an important aspect of drug delivery system. Microparticles were initially developed as carrier for vaccines & anticancer drugs. They have now been used to increase the efficiency of drug delivery system & improve release profile & for drug targeting. Microparticles have been proven to be ...
https://link.springer.com/chapter/10.1007/978-1-59259-427-6_6
In addition, other in vitro and in vivo results from microparticulate delivery systems for traditional cancer-fighting agents will be described. The more recent developments in gene delivery and utilization of targeted delivery and angiogenic factors will be discussed briefly with an emphasis on the possibilities that have yet to be realized.Author: Duane T. Birnbaum, Lisa Brannon-Peppas
https://www.sciencedirect.com/science/article/pii/S1742706118302484
Design and characterization of a novel kind of nanoparticle-in-microparticle drug delivery system with high stability and low drug release in the stomach. 3) Demonstration for the first time of the lack of benefit of only drug nanonization in protease inhibitors. 4) Design of a new protocol for oral administration of solid formulations in ...Author: Robin Augustine, Dana Levin Ashkenazi, Roni Sverdlov Arzi, Vita Zlobin, Rona Shofti, Alejandro Sosni...
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