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https://www.sciencedirect.com/science/article/pii/S0169409X00001125
These investigators also examined the utility of microdialysis for regional drug delivery of gentamicin to vitreous; with this approach, it was possible to effectively deliver therapeutically relevant concentrations to vitreous with avoidance of dramatic spikes in localized drug concentrations — a possible consequence of administration by ...Author: Kay D Rittenhouse, Gary M Pollack
https://www.sciencedirect.com/journal/advanced-drug-delivery-reviews/vol/45/issue/2
Read the latest articles of Advanced Drug Delivery Reviews at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature
https://www.ncbi.nlm.nih.gov/pubmed/11108976
Dec 15, 2000 · 1. Adv Drug Deliv Rev. 2000 Dec 15;45(2-3):229-41. Microdialysis and drug delivery to the eye. Rittenhouse KD(1), Pollack GM. Author information: (1)Preclinical Sciences, Bausch and Lomb Pharmaceuticals, Tampa, FL 33637, USA. The eye presents unique challenges in both the development of tools for elucidating drug disposition as well as for the development of modes of drug delivery for ...Author: Kay D Rittenhouse, Gary M Pollack
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575049/
The use of iontophoresis for cutaneous drug delivery of lidocaine significantly enhanced dermal penetration. Using an intact skin model, an iontophoretic patch operating at 0.15 mA/cm 2 resulted in a 40 fold increase in dermal lidocaine concentrations in comparison to passive drug delivery. When this system was applied to a sutured skin model ...Author: Heidi J. Holovics, Carter R. Anderson, Barry S. Levine, Ho-Wah Hui, Craig E. Lunte
https://www.researchgate.net/publication/12219101_Microdialysis_and_drug_delivery_to_the_eye
Microdialysis and drug delivery to the eye. ... Drug PK studies with microdialysis in tissues can also be combined with other types of PD measurements to obtain PK/PD relationships. Areas that ...
https://www.deepdyve.com/lp/elsevier/microdialysis-and-drug-delivery-to-the-eye-D0urCMDxd8
Dec 15, 2000 · Microdialysis and drug delivery to the eye Microdialysis and drug delivery to the eye Rittenhouse, Kay D; Pollack, Gary M 2000-12-15 00:00:00 The eye presents unique challenges in both the development of tools for elucidating drug disposition as well as for the development of modes of drug delivery for treatment of ocular diseases. In this paper, we present a discussion of the anatomical and ...
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