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https://path.azureedge.net/media/documents/DT_update_micro_patches_drug.pdf
One solution is transdermal drug delivery by microarray patch (also known as a microneedle patch), which consists of microscopic projections that painlessly penetrate the skin’s upper layers or mucosal tissues to administer medicines into the body.
https://www.path.org/resources/microarray-patches-for-drug-delivery/
Microarray Patches for Drug Delivery As part of PATH’s work in vaccine and pharmaceutical technologies, this technology update highlights our work in microarray patches (also known as microneedle patches) for drug delivery.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635881/
The development of new drug delivery methodologies focusing on precise targeting and control of the delivered payload has the potential to make significant contributions to the success of vaccines.Author: Fatemeh Nazly Pirmoradi, Ashish V Pattekar, Felicia Linn, Michael I Recht, Armin R Volkel, Qian Wang...
http://www.biopharminternational.com/microarray-applications-drug-discovery-and-development
Mar 01, 2005 · This technology has revolutionized drug discovery and development, as well. Pharmaceutical companies have adopted high-data-capacity microarrays in drug discovery research for applications such as target identification, target validation and pathway analysis, compound profiling, and toxicology studies.
https://path.org/programs/mdht/mapresources/
Microarray patches, also known as microneedle patches, consist of microscopic projections that are applied to the body like a small bandage, painlessly penetrating the skin’s outermost layer to deliver a drug or vaccine to the top layers of the skin.
https://www.3m.com/3M/en_US/drug-delivery-systems-us/technologies/microneedle/
Microneedle Drug Delivery Systems Technologies Hollow Microneedle Technology Offer a patient-friendly intradermal delivery solution for difficult-to-deliver biologics.
https://onlinelibrary.wiley.com/doi/full/10.1002/jin2.41
For oral vitamin D delivery, there are many challenges, including chemical instability and poor solubility in the gastrointestinal tract, as well as significant first‐pass metabolism, which prevents the drug from reaching the systemic circulation in its active form (Grossmann & Tangpricha, 2010). To overcome this oral bioavailability issues ...Author: Lalit K. Vora, Pradeep R. Vavia, Eneko Larrañeta, Steven E.J. Bell, Ryan F. Donnelly
https://www.sciencedirect.com/science/article/pii/S0927796X16300213
Therefore, controlled drug delivery is achievable by adjusting the polymeric composition of the MN array, or by modification of the MN fabrication process. Dissolving MNs present numerous advantages. The principal benefit is the low cost of polymeric materials and their relatively facile fabrication by micro-moulding processes at ambient temperatures, which should allow for straightforward industrial mass …Author: Eneko Larrañeta, Rebecca E.M. Lutton, A. David Woolfson, Ryan F. Donnelly
https://en.wikipedia.org/wiki/Magnetic_drug_delivery
Magnetic nanoparticle-based drug delivery is a means in which magnetic particles such as iron oxide nanoparticles are a component of a delivery vehicle for magnetic drug delivery, due to their easiness and simplicity with magnet-guidance.
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