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https://www.sciencedirect.com/topics/chemistry/micellar-drug
The micellar drug delivery systems provide advantages such as the following: less drug degradation and drug loss; optimized drug delivery; increased drug stability and bioavailability (Rangel-Yagui, Pessoa, & Tavares, 2005); fewer chances of drug side effects and toxic effects; and localized drug delivery to diseased and damaged body parts ...
https://hstalks.com/t/4153/micellar-drug-delivery/
Feb 27, 2020 · Click to launch & play an online audio visual presentation by Prof. Francesco Cellesi on Micellar drug delivery, part of a collection of online lectures.
https://www.ncbi.nlm.nih.gov/pubmed/17168771
Relevant properties discussed include micellar association, morphology, size and stability. These properties and characterization techniques are included to provide context for the known advantages and applications of polymeric micelles for drug delivery.Author: S. R. Croy, G. S. Kwon
https://www.sciencedirect.com/science/article/pii/S0168365903005030
Micellar formulations for drug delivery based on mixtures of hydrophobic and hydrophilic Pluronic® block copolymers. ... specifically related to drug delivery applications, is the ability to self-assemble in aqueous solutions into multimolecular aggregates having spherical, rod-like or lamellar morphologies. ...Author: Kyung T. Oh, Tatiana K. Bronich, Alexander Victorovich Kabanov
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801582/
In this review, we will discuss some of the investigation using polymeric micelles as nanocarriers for cutaneous deliveries in normal and dermatological disorder. In addition, selected examples from the literature have been included to demonstrate the mechanism of action of various drugs employing polymeric micellar-based drug delivery systems.
https://www.unmc.edu/pharmacy/faculty/pharmaceutical-sciences/docs/v5.pdf
used to prepare self-assembled polymer micelles for drug delivery,9,15,16 although the use of graft copolymers has been reported.17-19 For drug delivery purposes, the individual ure designed to be nimers a biodegradable20, 21 and/or have a low enough molecular mass (<~40 kDa) to be eliminated by renal clearance in order to avoid polymer
https://www.tandfonline.com/doi/abs/10.1517/17425240903380446
Jan 06, 2016 · Overcoming the barriers in micellar drug delivery: loading efficiency, in vivo stability, and micelle–cell interaction. Sungwon Kim Purdue University, Department of Industrial and Physical Pharmacy, West Lafayette, IN 47907, ...Author: Sungwon Kim, Yunzhou Shi, Ji Young Kim, Kinam Park, Ji-Xin Cheng
https://link.springer.com/article/10.1007/s12274-018-2134-5
Jul 11, 2018 · Redox-responsive polymer-drug conjugate micelles are excellent nanoscale vehicles for self-immolative intracellular drug delivery. To covalently connect the polymer and drug, disulfide-bearing linkers, such as 3,3’-dithiodipropionic acid (DDPA) and 4,4’-dithiodibutyric acid (DDBA), are used. In this paper, we report the influence of linker length on the therapeutic outcome of redox ...Author: Xuan Meng, Min Gao, Jian Deng, Di Lu, Aiping Fan, Dan Ding, Deling Kong, Zheng Wang, Yanjun Zhao
https://www.mdpi.com/journal/pharmaceutics/special_issues/micellar
Delivery of hydrophobic molecules and proteins has been an issue due to poor bioavailability following administration. Thus, micelle carrier systems are being investigated to improve drug …
https://pubs.rsc.org/en/content/articlelanding/2015/ra/c5ra02097b
We report that the polymer residue of hydrazone-containing pH-responsive polymeric conjugate micelles could induce considerable cytotoxicity in a model cell line (HeLa). However, there was no significant difference between the cytotoxicity of the residue of the model …Author: Yu Zhang, Min Gao, Chao Chen, Zheng Wang, Yanjun Zhao
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