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https://www.sciencedirect.com/topics/chemistry/micellar-drug
Some liposomal nanodrug systems, such as Doxil, Myocet, DaunoXome and Depocyte, and micellar drug systems such as Genexol-PM are already in clinical trials for cancer treatment. The major obstacle for nanocarrier drug delivery is its clearance by reticuloendothelial system due to …
https://hstalks.com/t/4153/micellar-drug-delivery/
Feb 27, 2020 · Click to launch & play an online audio visual presentation by Prof. Francesco Cellesi on Micellar drug delivery, part of a collection of online lectures.
https://www.sciencedirect.com/science/article/pii/S016836591101114X
In the past two decades, new drug exploration in terms of new chemical compounds was more and more challenging. In 2007, Somatuline Depot®, Lanreotide Acetate long-acting injection, was approved by the US Food and Drug Administration as a new molecular entity , indicating a significant role of the drug delivery system (DDS) in new drug exploration.Author: Jian Gong, Mei Wan (陳美婉) Chen, Ying (鄭穎) Zheng, Sheng Peng Wang, Yi Tao (王一濤) Wang
https://www.unmc.edu/pharmacy/faculty/pharmaceutical-sciences/docs/v5.pdf
used to prepare self-assembled polymer micelles for drug delivery,9,15,16 although the use of graft copolymers has been reported.17-19 For drug delivery purposes, the individual ure designed to be nimers a biodegradable20, 21 and/or have a low enough molecular mass (<~40 kDa) to be eliminated by renal clearance in order to avoid polymer
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306987/
A polymer micelle drug delivery system was developed that demonstrated encapsulation and stabilization of a wide variety of hydrophobic anticancer drugs. Drug release from stabilized micelles was determined to be pH dependent in vitro.Author: Jonathan Rios-Doria, Adam Carie, Tara Costich, Brian Burke, Habib Skaff, Riccardo Panicucci, Kevin S...
https://pubs.rsc.org/en/content/articlelanding/2019/tb/c9tb01221d#!
Benefitting from these novel functions, the supramolecular micellar drug delivery system exhibits great performances both in in vitro and in vivo evaluations. Doxorubicin (DOX)-loaded supramolecular micelles PAMAM–PBEP–PMP–FA/DOX are fast taken up by HepG2 cells and inhibit the tumor growth effectively in HepG2-tumor-bearing nude mice ...
https://www.ncbi.nlm.nih.gov/pubmed/17168771
Relevant properties discussed include micellar association, morphology, size and stability. These properties and characterization techniques are included to provide context for the known advantages and applications of polymeric micelles for drug delivery.Author: S. R. Croy, G. S. Kwon
https://www.hindawi.com/journals/jdd/2013/340315/
Oral administration is the most commonly used and readily accepted form of drug delivery; however, it is find that many drugs are difficult to attain enough bioavailability when administered via this route. Polymeric micelles (PMs) can overcome some limitations of the oral delivery acting as carriers able to enhance drug absorption, by providing (1) protection of the loaded drug from the harsh ...Author: Wei Xu, Peixue Ling, Tianmin Zhang
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