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https://www.researchgate.net/publication/49657582_Mathematical_modeling_of_polymer_erosion_Consequences_for_drug_delivery
Request PDF Mathematical modeling of polymer erosion: Consequences for drug delivery Bioerodible polymers have been extensively used as carriers for drug delivery …
https://www.sciencedirect.com/science/article/pii/S0378517310008975
A phenomenological model for polymer erosion was developed by Lee (1980), where the effect of drug solubility and loading on release from an eroding planar polymer matrix was modeled with moving diffusion and erosion fronts. When the velocities of these fronts were synchronized, a near zero-order drug release was observed.Author: Chelsea K. Sackett, Balaji Narasimhan
https://www.ncbi.nlm.nih.gov/pubmed/21130849
Oct 10, 2011 · Mathematical modeling of polymer erosion: consequences for drug delivery. Sackett CK(1), Narasimhan B. Author information: (1)Department of Chemical and Biological Engineering, Iowa State University, Ames, IA 50011, United States. Bioerodible polymers have been extensively used as carriers for drug delivery and as scaffolds for tissue engineering.Author: Chelsea K. Sackett, Balaji Narasimhan
https://www.researchgate.net/publication/49657582_Mathematical_modeling_of_polymer_erosion_Consequences_for_drug_delivery
Request PDF Mathematical modeling of polymer erosion: Consequences for drug delivery Bioerodible polymers have been extensively used as carriers for drug delivery …
https://www.sciencedirect.com/science/article/pii/S0168365914004507
More complex analyses of drug release from swellable systems are available that account for enthalpy balances and front synchronization , , non-uniform drug distributions within the polymer , , , , , geometric effects , multi-dimensional transport , time-dependent or concentration-dependent , , drug diffusion coefficients, and free volume . Based on these models, conditions to achieve zero order release of the drug …Author: Nicholas A. Peppas, Balaji Narasimhan
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518665/
Jan 10, 2013 · Erosion depends on the degradation, dissolution, and diffusion processes [ 27 ]. For PLGA, the dissolution of water-soluble oligomers up to nonamers [ 28 - 30] and of drug molecules is often assumed to occur with faster time scales than diffusion and polymer degradation in many mathematical models and is neglected.Author: Ashlee N. Ford Versypt, Ashlee N. Ford Versypt, Daniel W. Pack, Daniel W. Pack, Richard D. Braatz, R...
https://www.researchgate.net/publication/11969271_Mathematical_Models_Describing_Polymer_Dissolution_Consequences_for_Drug_Delivery
Polymer dissolution is an important phenomenon in polymer science and engineering that has found applications in areas like microlithography, controlled drug delivery, and plastics recycling. This review focuses on the modeling efforts to understand the physics of the drug release process from dissolving polymers.
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