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http://news.mit.edu/2015/implantable-drug-delivery-microchip-device-0629
Jun 29, 2015 · An implantable, microchip-based device may soon replace the injections and pills now needed to treat chronic diseases: Earlier this month, MIT spinout Microchips Biotech partnered with a pharmaceutical giant to commercialize its wirelessly controlled, implantable, microchip-based devices that store and release drugs inside the body over many years.
https://news.mit.edu/2015/implantable-drug-delivery-microchip-device-0629?fbclid=IwAR2MyjrCVayERAlTZjn_7xFhQlugrMNCPz_TVKyPH6J9_YJwIViLEAZdFp8
MIT spinoff Microchips Biotech, founded by Michael Cima and Robert Langer, has partnered with a Teva Pharmaceutical to commercialize its wirelessly controlled, implantable microchip-based devices that store and release drugs inside the body over many years.
https://www.webmd.com/osteoporosis/news/20120216/drug-delivery-microchip
Feb 16, 2012 · An experimental, implanted drug-delivery microchip that releases medication on command from an external wireless control could one day free patients from daily injections and improve treatment ...Author: Salynn Boyles
http://www.thepharmajournal.com/vol1Issue10/Issue_dec_2012/1.1.pdf
Microchip drug delivery system is the most wonderful system of delivering the drug for a great span of time without the intervention of the patient to whom it is fixed. It consists of varied number of sockets containing drug (generally ranging from 50-300) which release the drug …
http://news.mit.edu/1999/microchipcom
The microchip could be integrated with a tiny power supply and controlled by a microprocessor, remote control, or biosensors. This microchip technology has potential uses in areas such as medical diagnostics, chemical detection, combinatorial chemistry, drug delivery, cosmetics, and entertainment.
https://www.hindawi.com/journals/bmri/2016/1743472/
Design and Components. Implanted microchips enable on-demand drug release [5, 12, 13]. Solid silicon microchips consist of hundreds of reservoirs filled with up to 1 mL drugs in an aseptic solid, liquid, or gel filing [14, 15].Author: Adam E. M. Eltorai, Henry Fox, Emily McGurrin, Stephanie Guang
http://news.mit.edu/2012/wireless-drug-delivery-0216
“It fulfills the promise of polymer drug delivery and the incredible sophistication of microchip capabilities.” Once a version of the implant that can carry a larger number of doses is ready, MicroCHIPS plans to seek approval for further clinical trials, Farra says.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914739/
Jun 07, 2016 · In 1998, the US Patent “Microchip Drug Delivery Devices” was awarded to Santini Jr. et al., which first outlined the parameters of a multireservoir microchip system with an active release system . In 1999, Santini Jr. et al. debuted the first electrochemically activated drug delivery microchip .Author: Adam E. M. Eltorai, Henry Fox, Emily McGurrin, Stephanie Guang
https://be.mit.edu/research-areas/drug-delivery
Drug Delivery Drug delivery is the field of resarch to develop new technologies and approaches to transport drugs through the body. In BE, there are professors studying many aspects of this field including some engineering antibodies to target tumors and others developing chemotherapeutics for selective killing of tumor cells.
https://dmse.mit.edu/people/michael-j-cima
Cima's research includes advanced forming technologies for complex macro and micro devices, such as colloid science, MEMS and other micro components for medical devices that are used for drug delivery and diagnostics, as well as high-throughput development methods for formulations of materials and pharmaceutical formulations.
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