Mathematical Modeling Of Drug Delivery

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Mathematical modeling of drug delivery - ScienceDirect

    https://www.sciencedirect.com/science/article/pii/S0378517308006169
    The mathematical modeling of drug delivery has a significant potential to facilitate product development in the future and to help understanding complex pharmaceutical dosage forms. Due to the advances in information technology the accuracy of these models steadily increases and …Author: J. Siepmann, F. Siepmann

Mathematical modeling of drug delivery.

    https://www.ncbi.nlm.nih.gov/pubmed/18822362
    Dec 08, 2008 · Due to the significant advances in information technology mathematical modeling of drug delivery is a field of steadily increasing academic and industrial importance with an enormous future potential. The in silico optimization of novel drug delivery systems can be expected to significantly increase in accuracy and easiness of application.Author: J. Siepmann, F. Siepmann

Mathematical modeling of drug delivery - ResearchGate

    https://www.researchgate.net/publication/23285105_Mathematical_modeling_of_drug_delivery
    Due to the significant advances in information technology mathematical modeling of drug delivery is a field of steadily increasing academic and industrial importance with an enormous future potential.

Mathematical and computational modeling of nano-engineered ...

    https://www.sciencedirect.com/science/article/pii/S0168365919303244
    Mathematical and numerical simulations are an integral part of research in DDSs. These models help predict drug delivery efficiency and therapeutic efficacy of the nanomedicines [].Various modeling techniques have been proposed to simulate DDSs of interest at different levels of details (see Fig. 1A and Table 1).Particle-based modeling employs finer space-time scales (length scales on the ...Author: Milad Shamsi, Amir Mohammadi, Mohammad K.D. Manshadi, Amir Sanati-Nezhad

Mathematical Modeling of Drug Delivery from ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518665/
    Jan 10, 2013 · This review aims to highlight mechanistic, mathematical models that address the role of autocatalysis in the mass transport and chemical reaction phenomena of drug delivery from PLGA microspheres. The place of these types of models in the broader context of mathematical models for polymeric drug delivery systems is illustrated in Fig. 3.Author: Ashlee N. Ford Versypt, Ashlee N. Ford Versypt, Daniel W. Pack, Daniel W. Pack, Richard D. Braatz, R...

Mathematical Modeling and Optimization of Drug Delivery ...

    https://clincancerres.aacrjournals.org/content/11/2/826
    Jan 15, 2005 · Although intratumoral delivery of paclitaxel to the whole tumor at different loads and rates has already been achieved, determining an optimal release mode of paclitaxel for tumor eradication remains difficult. This study set out to rationally design such an optimal microsphere release mode based on mathematical modeling.Author: Abraham Rami Tzafriri, Elyakum Itzhak Lerner, Moshe Flashner-Barak, Michael Hinchcliffe, Eli Ratner,...

Journal of Controlled Release - MIT

    http://web.mit.edu/braatzgroup/mathematical_modeling_of_drug_delivery_from_autocatalytically_degradable_plga_microspheres_a_review.pdf
    Review Mathematical modeling of drug delivery from autocatalytically degradable PLGA microspheres — A review☆ Ashlee N. Ford Versypt a,b, Daniel W. Pack a,c, Richard D. Braatz a,b,⁎ a Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA b Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge ...

Pharmaceutics Free Full-Text Mathematical Modeling of ...

    https://www.mdpi.com/1999-4923/11/3/140/htm
    Mathematical modeling of the release data allowed simultaneous determination of drug permeability and interfacial binding to the bilayer . A particular study concerned the release of …Author: Constantin Mircioiu, Victor Voicu, Valentina Anuta, Andra Tudose, Christian Celia, Donatella Paolino...

Mathematical Modeling for Pharmaco-Kinetic and -Dynamic ...

    https://www.hindawi.com/journals/scientifica/2019/9153876/
    Predicting pharmacokinetics, based on the theory of dynamic systems, for an administered drug (whether intravenously, orally, intramuscularly, etc.), is an industrial and clinical challenge. Often, mathematical modeling of pharmacokinetics is preformed using only a measured concentration time profile of a drug administered in plasma and/or in blood. Yet, in dynamic systems, mathematical ...Author: Grigorios P. Panotopoulos, Ziyad S. Haidar

Role of Mathematical Modeling in Controlled Drug Delivery ...

    https://www.researchgate.net/publication/242784947_Role_of_Mathematical_Modeling_in_Controlled_Drug_Delivery
    Mathematical modeling of controlled drug delivery can help to provide a scientific knowledge base concerning the mass transport mechanisms that are involved in the control of drug release.

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