Lipid-Based Nanoparticles For Nucleic Acid Delivery

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Lipid-based Nanoparticles for Nucleic Acid Delivery ...

    https://link.springer.com/article/10.1007/s11095-006-9180-5
    Jan 25, 2007 · Lipid-based colloidal particles have been extensively studied as systemic gene delivery carriers. The topic that we would like to emphasize is the formulation/assembly of lipid-based nanoparticles (NP) with diameter under 100 nm for delivering nucleic acid in vivo. NP are different from cationic lipid–nucleic acid complexes (lipoplexes) and are vesicles composed of lipids and …Author: Weijun Li, Weijun Li, Francis C. Szoka

Lipid-based nanoparticles for nucleic acid delivery.

    https://www.ncbi.nlm.nih.gov/pubmed/17252188
    Lipid-based colloidal particles have been extensively studied as systemic gene delivery carriers. The topic that we would like to emphasize is the formulation/assembly of lipid-based nanoparticles (NP) with diameter under 100 nm for delivering nucleic acid in vivo.Author: Weijun Li, Weijun Li, Francis C. Szoka

Lipid-based Nanoparticles for Nucleic Acid Delivery ...

    https://www.researchgate.net/publication/6551888_Lipid-based_Nanoparticles_for_Nucleic_Acid_Delivery
    Lipid-based colloidal particles have been extensively studied as systemic gene delivery carriers. The topic that we would like to emphasize is the formulation/assembly of lipid-based nanoparticles ...

Nucleic acid-mediated intracellular protein delivery by ...

    https://www.sciencedirect.com/science/article/pii/S0142961214003883
    Intracellular protein delivery has potential biotechnological and therapeutic application, but remains technically challenging. In contrast, a plethora of nucleic acid carriers have been developed, with lipid-based nanoparticles (LNPs) among the most clinically advanced reagents for oligonucleotide delivery.Author: Ahmed Atef Eltoukhy, Delai Chen, Omid Veiseh, Jeisa Pelet, Hao Yin, Yizhou Dong, Daniel Griffith And...

Lipid-Based Nanoparticles for Drug-Delivery Systems ...

    https://www.sciencedirect.com/science/article/pii/B9780128140338000084
    Lipid-based systems also inhibit API oxidation, decomposition, and degradation, while storage and delivery are enhanced . The major advantage of lipid-based drug-delivery systems is the feasibility of transport across the gut, GIT, blood vessels, and blood–brain barrier . Lipid-based drug delivery is an ever-growing area.Author: Raj Kumar, Raj Kumar

Lipid Nanoparticles for Gene Delivery

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006671/
    SNALP technology from Tekmira Pharmaceuticals, Inc. is one of the most widely used lipid-based nucleic acid delivery approaches for systemic administration in clinical trials. Lipid vesicles encapsulating nucleic acids are formed instantaneously by mixing lipids dissolved in ethanol with an aqueous solution of nucleic acids in a controlled ...Author: Yi Zhao, Leaf Huang

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