Lysosomal Delivery Systems Inc

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Lysosomal Therapeutics, Inc. (LTI)

    https://www.lysosomaltx.com/
    Lysosomal Therapeutics Inc. (LTI) discovers and develops new therapies for patients with severe neurological diseases. Our strategy leverages the clinically-validated link between lysosome-based genetic disorders and neurodegenerative diseases to establish a unique and effective platform for novel d

Lysosomal Delivery System Inc - Manta

    https://www.manta.com/c/mm04l4p/lysosomal-delivery-system-inc
    Lysosomal Delivery System Inc is a privately held company in Minneapolis, MN and is a Single Location business. Categorized under Business Research Services. Our records show it was established in 1992 and incorporated in Minnesota. Current estimates show this company has an annual revenue of 840000 and employs a staff of approximately 12.Employees: 12

ABOUT US — Lysosomal Therapeutics, Inc. (LTI)

    https://www.lysosomaltx.com/about-us
    ABOUT US . Lysosomal Therapeutics Inc. (LTI) is dedicated to innovative, research and development in the field of neurodegeneration. Our strategy leverages the genetically and clinically validated link between lysosomal disorders and neurodegenerative diseases to establish a unique and effective platform for novel drug discovery.

A Sensitive and Quantitative Technique for Detecting ...

    https://www.sciencedirect.com/science/article/pii/S1074552111002043
    We sought to develop a sensitive and quantitative technique capable of monitoring the entire flux of autophagy involving fusion of lysosomal membranes. We observed the accumulation inside lysosomal compartments of Keima, a coral-derived acid-stable fluorescent protein that emits different-colored signals at acidic and neutral pHs.Author: Hiroyuki Katayama, Takako Kogure, Noboru Mizushima, Tamotsu Yoshimori, Atsushi Miyawaki

Lysosomal sequestration of amine-containing drugs ...

    https://www.ncbi.nlm.nih.gov/pubmed/17117426
    Kaufmann AM(1), Krise JP. Author information: (1)Department of Pharmaceutical Chemistry, The University of Kansas, 2095 Constant Avenue, Lawrence, Kansas 66047, USA. Amine-containing drugs represent a very important class of therapeutic agents, with the majority of …Author: Allyn M. Kaufmann, Jeffrey P. Krise

Strategies for Delivery of Therapeutics into the Central ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969788/
    Jun 01, 2012 · Strategies for Delivery of Therapeutics into the Central Nervous System for Treatment of Lysosomal Storage Disorders. ... The later two approaches are being pursued at the time by coupling therapeutic agents to affinity moieties and drug delivery systems capable of targeting these natural transport routes. This approach is particularly ...Author: Silvia Muro

Lysosome - Wikipedia

    https://en.wikipedia.org/wiki/Lysosomal
    The production of lysosomal proteins suggests one method of lysosome sustainment. Lysosomal protein genes are transcribed in the nucleus. mRNA transcripts exit the nucleus into the cytosol, where they are translated by ribosomes. The nascent peptide chains are translocated into the rough endoplasmic reticulum, where they are modified.

Drug Delivery to Lysosomal Storage Diseases authorSTREAM

    http://www.authorstream.com/Presentation/phani.thanneru-1598552-drug-delivery-lysosomal-storage-diseases/
    Drug Delivery to Lysosomal Storage Diseases - authorSTREAM Presentation. Slide 18: Enzyme Delivery across the Blood-Brain Barrier(BBB): 1.BBB is characterized by a layer endothelial cells, joined by tight junction 2. this restricts transport of bulk recombinant enzymes across brain Methods used to by pass the barrier are 1 .opening BBB by infusion of hypo osmotic solution (arabinose) into the ...

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