We have collected information about Liposomal Formulations For Nucleic Acid Delivery for you. Follow the links to find out details on Liposomal Formulations For Nucleic Acid Delivery.
https://www.researchgate.net/publication/254371461_Liposomal_Formulations_for_Nucleic_Acid_Delivery
[Show full abstract] for efficient nucleic acid delivery in vivo. Given the many advantages of liposomes for drug delivery, alternative liposome formulations of nucleic acid are discussed.Author: Ian Maclachlan
http://arbutusbio.com/docs/Liposome_Formulations_Proof_for_Distribution.pdf
9.1 liposomes for the delivery of nucleic acid drugs Liposomes are artificial vesicles made up of one or more bilayers of amphipathic lipid encap- sulating an equal number of internal aqueous compartments.
http://repository-tnmgrmu.ac.in/2627/1/26091390%20Noveen%20Kumar%20Reddy%20Konda.pdf
FORMULATION AND EVALUATION OF LIPOSOMAL DRUG DELIVERY SYSTEM FOR DOXORUBICIN HYDROCHLORIDE ... DNA Deoxyribose nucleic acid 6. DSPC Distearoyl phosphatidyl choline 7. EE Encapsulation efficiency 8. FTIR Fourier Transform Infrared …
https://lens.org/016-009-753-615-459
There are provided liposomes, comprising cationic lipids, a membrane stabilizing lipid and at least one lipid conjugated to a polyethylene glycol (PEG) derivative, in particular PEG-amine, the liposomes are coated with a glycosaminoglycan, in particular, Hyaluronic Acid (HA), compositions comprising the same, methods for their preparation and uses thereof for the efficient delivery of nucleic ...Author: Dan Peer
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/liposomal-drug-delivery
This chapter focuses on liposomal drug delivery systems, the limitations of conventional formulations as cytosolic delivery vehicles for macromolecules, and potential solutions achieved by the utilization of a bacterial mechanism of cell invasion. The mechanism by which liposomes interact with cells is briefly examined and a discussion ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723796/
Jul 24, 2019 · In the last years the rapid development of Nucleic Acid Based Drugs (NABDs) to be used in gene therapy has had a great impact in the medical field, holding enormous promise, becoming “the latest generation medicine” with the first ever siRNA-lipid based formulation approved by the United States Food and Drug Administration (FDA) for human use, and currently on the market under the …Author: Anna Angela Barba, Sabrina Bochicchio, Annalisa Dalmoro, Gaetano Lamberti
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664963/
Dec 01, 2015 · Advances and Challenges of Liposome Assisted Drug Delivery. ... mucoadhesive and nucleic acid-based delivery systems. For example, ... Liposomal formulations have demonstrated significant therapeutic advantages for a multitude of biomedical applications, however the major reasons for the bottleneck have been attributed to issues surrounding ...Author: Lisa Sercombe, Tejaswi Veerati, Tejaswi Veerati, Fatemeh Moheimani, Sherry Y. Wu, Anil K. Sood, Susa...
https://www.nature.com/articles/s41598-017-09555-w
Aug 25, 2017 · Cancer-targeted Nucleic Acid Delivery and Quantum Dot Imaging Using EGF Receptor Aptamer-conjugated Lipid Nanoparticles ... we examined …Author: Min Woo Kim, Hwa Yeon Jeong, Seong Jae Kang, Moon Jung Choi, Young Myoung You, Chan Su Im, Tae Sup L...
https://www.sciencedirect.com/science/article/pii/S0169409X12002980
Liposomal drug delivery systems: ... A number of general principles have emerged from the large and rapidly growing literature in the field of nucleic acid delivery: ... therapeutic activity, and toxicity of pegylated liposomal doxorubicin formulations in murine breast cancer. Biochim. Biophys. Acta, 1663 (2004), pp. 167-177.Author: Theresa M. Allen, Pieter R. Cullis
https://www.liebertpub.com/doi/10.1089/104454902762053828
Jul 06, 2004 · Optimization of cationic liposomal complexes for in vivo applications and therapeutics is complex involving many distinct components. These components include nucleic acid purification, plasmid design, formulation of the delivery vehicle, administration route and schedule, dosing, detection of gene expression, and others.Author: Nancy Smyth Templeton
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