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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066571/
Dec 15, 2010 · Despite some favorable investigations into the use of anionic liposomes for gene delivery, there are some potential downfalls associated with systemic delivery that must be further explored. Some studies have indicated that, upon exposure to certain plasma lipoproteins, destabilization and leakage of liposomal contents can occur.Author: Daniel A. Balazs, Wt. Godbey
https://www.hindawi.com/journals/jdd/2011/326497/
Liposomes are often used to deliver a molecular cargo such as DNA for therapeutic benefit. The lipids used to form such lipoplexes can be cationic, anionic, neutral, or a mixture thereof. Herein physical packing parameters and specific lipids used for gene delivery will be discussed, with lipids classified according to overall charge.Author: Daniel A. Balazs, Wt. Godbey
https://www.nature.com/articles/s41417-019-0141-7
Nov 02, 2019 · Liposomes are one of the most widely investigated carriers for CRISPR/Cas9 delivery. The surface properties of liposomal carriers, including …Author: Shuai Zhen, Shuai Zhen, Xu Li, Xu Li
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/liposomal-drug-delivery
Liposomal drug delivery systems are very effective in the delivery of vaccines and genes due to their adjuvant property and targeting ability which elicit the immune response of the body through antibody formation and corrected gene inputs. Along with this, the mechanism of vaccine and gene delivery is …
https://www.slideshare.net/DurgaBhavani60/liposomal-gene-delivery-system
Jul 14, 2019 · LIPOSOMAL GENE DELIVERY SYSTEMS: INTRODUCTION: Liposomes have been explored as a delivery system for DNA as early as in 1979. The encapsulation of plasmid DNA into liposomes and the introduction of poliovirus RNA and SV40 DNA into cells via liposomes were reported between 1979 and 1980. These are vesicles that can easily merge with the cell ...
https://www.researchgate.net/publication/12950633_Liposomes_as_a_gene_delivery_system
Liposomes as a gene delivery system. ... The characteristics of liposomal systems of anticancer drug delivery designed at Blokhin Russian Oncological Scientific Centre is given in the article.
https://www.sciencedirect.com/science/article/pii/S0169409X12002980
Liposomal drug delivery systems: From concept to clinical applications ... the delivery of gene medicines, and the delivery of anesthetics and anti-inflammatory drugs. A number of liposomes (lipidic nanoparticles) are on the market, and many more are in the pipeline. Lipidic nanoparticles are the first nanomedicine delivery system to make the ...Author: Theresa M. Allen, Pieter R. Cullis
https://www.hindawi.com/journals/bmri/2014/934605/
Advancement in the gene delivery system have resulted in clinical successes in gene therapy for patients with several genetic diseases, such as immunodeficiency diseases, X-linked adrenoleukodystrophy (X-ALD) blindness, thalassemia, and many more. Among various delivery systems, liposomal mediated gene delivery route is offering great promises for gene therapy. This review is an attempt to ...Author: Shyamal Kumar Kundu, Shyamal Kumar Kundu, Ashish Ranjan Sharma, Sang-Soo Lee, Garima Sharma, C. Geor...
https://www.naturalmedicinejournal.com/blog/secret-effective-liposomal-delivery
A properly manufactured liposomal product will fuse with cell membranes and facilitate efficient intracellular delivery. The lipid membranes of the liposome, usually comprised mostly of phosphatidyl choline, fuse with the cell membrane, supporting effective cell membrane function and signaling throughout the body.
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