Lipid Mediated Gene Delivery

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Lipid-mediated delivery of RNA is more efficient than ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2849731/
    Apr 15, 2010 · The design of appropriate gene delivery systems is essential for the successful application of gene therapy to clinical medicine. Cationic lipid-mediated delivery is a viable alternative to viral vector-mediated gene delivery in applications where transient gene expression is desirable.Author: S. Zou, K. Scarfo, M.H. Nantz, J.G. Hecker

How Cationic Lipid Mediated Transfection Works Thermo ...

    https://www.thermofisher.com/us/en/home/references/gibco-cell-culture-basics/transfection-basics/gene-delivery-technologies/cationic-lipid-mediated-delivery/how-cationic-lipid-mediated-transfection-works.html
    Cationic lipid-mediated delivery is a fast, simple, and reproducible means for easily introducing DNA, RNA, siRNA, or oligonucleotides into eukaryotic cells. It allows the highly efficient transfection of a broad range of cell types, including adherent, suspension, and insect cells, as well as primary cultures.

Lipid Nanoparticles for Gene Delivery

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006671/
    Among various nonviral gene vectors, lipid nanoparticles are an ideal platform for the incorporation of safety and efficacy into a single delivery system. In this chapter, we highlight current lipidic vectors that have been developed for gene therapy of tumors and other diseases.Author: Yi Zhao, Leaf Huang

Lipid-mediated gene delivery to the skin - ScienceDirect

    https://www.sciencedirect.com/science/article/pii/S0928098711000984
    Therefore, delivery enhancing techniques are often employed in combination with liposomes to increase the transfection efficiency. In the following section, we will describe the use of lipid-mediated gene delivery in combination with delivery enhancing techniques for various cutaneous purposes.Author: Barbara Geusens, Tine Strobbe, Stefanie Bracke, Peter Dynoodt, Niek Sanders, Mireille Van Gele, Jo L...

Cationic lipid-mediated delivery of proteins enables ...

    https://www.nature.com/articles/nbt.3081
    Oct 30, 2014 · Figure 5: DNA sequence specificity of Cas9-mediated endogenous gene cleavage in cultured human cells by plasmid transfection or by cationic lipid–mediated protein:sgRNA delivery using …Author: John A. Zuris, John A. Zuris, David B. Thompson, David B. Thompson, Yilai Shu, John P. Guilinger, Jo...

Lipid nanoparticle-mediated efficient delivery of CRISPR ...

    https://www.nature.com/articles/am2017185
    Oct 27, 2017 · Our work contributes to synthesize a vehicle based on lipid nanoparticles, which can effectively deliver Cas9/sgRNA-fused plasmid DNA in vitro and …Author: Lingmin Zhang, Lingmin Zhang, Peng Wang, Qiang Feng, Nuoxin Wang, Zitian Chen, Yanyi Huang, Wenfu Zh...

LIPID-MEDIATED GENE DELIVERY TO THE SKIN Request PDF

    https://www.researchgate.net/publication/51072402_Lipid-mediated_gene_delivery_to_the_skin
    Lipid-mediated gene delivery to the skin. ... lipid-based delivery vehicles demonstrate very promising results for DNA delivery into and through the skin, especially for cutaneous vaccination ...

Liposomes for Use in Gene Delivery

    https://www.hindawi.com/journals/jdd/2011/326497/
    The use of a cation is a recurring theme for virtually all chemically mediated gene delivery vectors, including polymers, lipids, and nondegradable nanoparticles. Between 8–18 carbons commonly comprise the hydrocarbon tails of lipids used for gene delivery. The tails are typically saturated, but a single double bond is occasionally seen.Author: Daniel A. Balazs, Wt. Godbey

Lipid-mediated gene delivery to the skin. Semantic Scholar

    https://www.semanticscholar.org/paper/Lipid-mediated-gene-delivery-to-the-skin.-Geusens-Strobbe/5f3a50914044cf68792ea66927bcb08957da0dcd
    @article{Geusens2011LipidmediatedGD, title={Lipid-mediated gene delivery to the skin.}, author={Barbara Geusens and Tine Strobbe and Stefanie Bracke and Peter Dynoodt and Niek N. Sanders and Mireille van Gele and Jo Lambert}, journal={European journal of pharmaceutical sciences : official journal of ...

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