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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2849731/
Apr 15, 2010 · The design of appropriate gene delivery systems is essential for the successful application of gene therapy to clinical medicine. Cationic lipid-mediated delivery is a viable alternative to viral vector-mediated gene delivery in applications where transient gene expression is desirable.Author: S. Zou, K. Scarfo, M.H. Nantz, J.G. Hecker
https://www.nature.com/articles/nbt.3081
Oct 30, 2014 · Zuris, J., Thompson, D., Shu, Y. et al. Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo. Nat Biotechnol 33, 73–80 (2015 ...Author: John A. Zuris, John A. Zuris, David B. Thompson, David B. Thompson, Yilai Shu, John P. Guilinger, Jo...
https://www.researchgate.net/publication/234086701_Nonviral_Cationic_Lipid-Mediated_Delivery_of_mRNA
Cationic lipid-mediated delivery is an alternative to viral vector-mediated gene delivery. Lipid-mediated delivery of DNA or mRNA is usually more rapid than viral-mediated delivery, offers a ...
https://www.thermofisher.com/us/en/home/references/gibco-cell-culture-basics/transfection-basics/gene-delivery-technologies/cationic-lipid-mediated-delivery/how-cationic-lipid-mediated-transfection-works.html
Cationic lipid-mediated delivery is a fast, simple, and reproducible means for easily introducing DNA, RNA, siRNA, or oligonucleotides into eukaryotic cells. It allows the highly efficient transfection of a broad range of cell types, including adherent, suspension, and insect cells, as well as primary cultures.
https://www.nature.com/articles/am2017185
Oct 27, 2017 · Our work contributes to synthesize a vehicle based on lipid nanoparticles, which can effectively deliver Cas9/sgRNA-fused plasmid DNA in vitro and …Author: Lingmin Zhang, Lingmin Zhang, Peng Wang, Qiang Feng, Nuoxin Wang, Zitian Chen, Yanyi Huang, Wenfu Zh...
https://endpts.com/sp/addressing-key-challenges-of-lipid-mediated-delivery-systems-for-mrna-through-innovation/
Mar 09, 2020 · 2020 is anticipated to be an exciting year for the field of messenger RNA (mRNA) therapeutics. Systemic delivery of lipid nanoparticle formulated mRNA (i.e. …Author: Arcturus Therapeutics Team
https://www.sciencedirect.com/science/article/pii/S0378517320300156
Nanostructured lipid carriers-mediated brain delivery of carbamazepine for improved in vivo anticonvulsant and anxiolytic activity. Author links open overlay panel Namrah Khan a Fawad Ali Shah a Isra Rana a Muhammad Mohsin Ansari a Fakhar ud Din b Syed Zaki Husain Rizvi a Waqar Aman c Gwan-Yeong Lee d Eun-Sun Lee d Jin-Ki Kim d Alam Zeb a.Author: Namrah Khan, Fawad Ali Shah, Isra Rana, Muhammad Mohsin Ansari, Fakhar ud Din, Syed Zaki Husain Rizv...
https://arcturusrx.com/proprietary-technologies/lunar/
Unlike other lipid-mediated delivery systems, LUNAR can deliver nucleic acids to a range of clinically important cells and tissues. LUNAR lipids are pH-sensitive and biodegradable, causing minimal lipid accumulation in cells after multiple dosing. First-generation LUNAR formulations show a wide therapeutic index in preclinical studies.
https://www.sciencedirect.com/science/article/pii/S0928098711000984
Therefore, delivery enhancing techniques are often employed in combination with liposomes to increase the transfection efficiency. In the following section, we will describe the use of lipid-mediated gene delivery in combination with delivery enhancing techniques for various cutaneous purposes.Author: Barbara Geusens, Tine Strobbe, Stefanie Bracke, Peter Dynoodt, Niek Sanders, Mireille Van Gele, Jo L...
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