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https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/lipid-based-drug-delivery-system
The lipid-based drug delivery systems (SLN, NLCs, LDC) are the most promising areas of research in drug delivery system and have shown better encapsulation efficiency and drug loading.
https://www.hindawi.com/journals/jphar/2014/801820/
Lipid-based drug delivery systems provide the vast array of possibilities to formulations as they potentially increase the bioavailability of number of poorly soluble drugs along with the formulations of physiologically well tolerated class.Author: Kent Jørgensen, Jesper Davidsen, Charlotte Vermehren, Sven Frøkjær, Ole G. Mouritsen
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590796/
May 19, 2014 · Lipid-based drug delivery systems (LBDDS) are one of the emerging technologies designed to address challenges like the solubility and bioavailability of poorly water-soluble drugs. Lipid-based formulations can be tailored to meet a wide range of product requirements dictated by disease indication, route of administration, cost consideration, product stability, toxicity, and efficacy.Author: Kent Jørgensen, Jesper Davidsen, Charlotte Vermehren, Sven Frøkjær, Ole G. Mouritsen
https://drug-dev.com/lipid-based-delivery-are-lipid-based-drug-delivery-systems-in-your-formulation-toolbox/
Lipid-based drug delivery systems (LBDDS) is a wide-ranging designation for formulations containing a dissolved or suspended drug in lipidic excipients. Lipids are esters of fatty acids – lipophilic hydrocarbon chains linked to a hydrophilic group like glycerol, polyglycerol, or polyalcohol (Figure 1).
http://www.americanpharmaceuticalreview.com/Featured-Articles/341191-Why-Consider-a-Lipid-Based-Drug-Delivery-System-LBDDS/
Aug 15, 2017 · Approximately 90 percent of molecules in the discovery pipeline, and approximately 40 percent of drugs with market approval, are poorly water soluble. 2 Advanced delivery technologies, like lipid-based systems, are an alternative solution to safely and effectively deliver the proper therapeutic dose to patients. Unlike conventional tablets or powder-filled capsules, LBDDS can present the drug ...Author: John Lipari
https://www.researchgate.net/publication/275064687_Lipid-Based_Drug_Delivery_Systems
Lipid-based drug delivery systems (LBDDS) are one of the emerging technologies designed to address challenges like the solubility and bioavailability of poorly water-soluble drugs. Lipid-based formulations can be tailored to meet a wide range of product requirements dictated by …
https://www.sciencedirect.com/science/article/pii/S2211383513000919
Review Oral lipid-based drug delivery systems – an overview 1. Introduction. Drawbacks to intravenous administration, including extravasation of drug or blood,... 2. Drug absorption. In practice, lipid formulations can be obtained as a result of blending... 3. Lipid excipients. A wide range of ...Author: Sandeep Kalepu, Mohanvarma Manthina, Veerabhadhraswamy Padavala
https://www.hindawi.com/journals/ap/2014/574673/
Vesicular drug delivery system can be defined as highly ordered assemblies consisting of one or more concentric bilayers formed as a result of self-assembling of amphiphilic building blocks …Author: Shikha Jain, Vikas Jain, S. C. Mahajan
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178953/
Lipid based formulations such as microemulsion and Self Microemulsifying drug delivery systems are expected to increase the oral bioavailability as evidenced by the increased intestinal permeation.
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