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https://www.sciencedirect.com/science/article/pii/S2211383513000919
The availability of novel lipid excipients with acceptable regulatory and safety profiles coupled with their ability to enhance oral bioavailability has helped in the development of lipid based formulations as a means for drug delivery. Lipid-based drug delivery (LBDD) systems have gained much importance in the recent years due to their ability ...Author: Sandeep Kalepu, Mohanvarma Manthina, Veerabhadhraswamy Padavala
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590796/
May 19, 2014 · The principle objective of formulation of lipid-based drugs is to enhance their bioavailability. The use of lipids in drug delivery is no more a new trend now but is still the promising concept. Lipid-based drug delivery systems (LBDDS) are one of the ...Author: Kent Jørgensen, Jesper Davidsen, Charlotte Vermehren, Sven Frøkjær, Ole G. Mouritsen
https://www.hindawi.com/journals/jphar/2014/801820/
The principle objective of formulation of lipid-based drugs is to enhance their bioavailability. The use of lipids in drug delivery is no more a new trend now but is still the promising concept. Lipid-based drug delivery systems (LBDDS) are one of the emerging technologies designed to address challenges like the solubility and bioavailability of poorly water-soluble drugs. Lipid-based ...Author: Kent Jørgensen, Jesper Davidsen, Charlotte Vermehren, Sven Frøkjær, Ole G. Mouritsen
https://www.sciencedirect.com/book/9780323527293/lipid-based-nanocarriers-for-drug-delivery-and-diagnosis
Lipid-Based Nanocarriers for Drug Delivery and Diagnosis explores the present state of widely used lipid-based nanoparticulate delivery systems, such as solid lipid nanoparticles (SLN), nanostructured lipid carriers (NLC), nanoliposomes, micelles, nanoemulsions, nanosuspensions and lipid nanotubes. The various types of lipids that can be ...
https://drug-dev.com/lipid-based-delivery-are-lipid-based-drug-delivery-systems-in-your-formulation-toolbox/
INTRODUCTION TO LIPID-BASED DOSAGE FORMS. Lipid-based drug delivery systems (LBDDS) is a wide-ranging designation for formulations containing a dissolved or suspended drug in lipidic excipients. Lipids are esters of fatty acids – lipophilic hydrocarbon chains linked to a hydrophilic group like glycerol, polyglycerol, or polyalcohol (Figure 1).
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406477/
Feb 13, 2019 · Diagram of drug delivery system for oral lipid-based formulation (LBF) drug and its absorption. LBF drug enters the stomach where gastric lipase hydrolysed and stabilised the drug in the stomach, due to the presence of its excipient and surfactant. An excipient is defined as the drug carrier, usually lipids that help to solubilise drugs.Author: Danial Efendy Goon, Siti Hamimah Sheikh Abdul Kadir, Normala Ab Latip, Sharaniza Ab. Rahim, Musalmah...
http://www.americanpharmaceuticalreview.com/Featured-Articles/341191-Why-Consider-a-Lipid-Based-Drug-Delivery-System-LBDDS/
Aug 15, 2017 · Approximately 90 percent of molecules in the discovery pipeline, and approximately 40 percent of drugs with market approval, are poorly water soluble. 2 Advanced delivery technologies, like lipid-based systems, are an alternative solution to safely and effectively deliver the proper therapeutic dose to patients. Unlike conventional tablets or powder-filled capsules, LBDDS can present the drug ...Author: John Lipari
https://www.tandfonline.com/doi/full/10.1080/03639045.2017.1342654
Mar 27, 2014 · Lipid-based drug delivery systems (LBDDS) are one of the most studied bioavailability enhancement technologies and are utilized in a number of U.S. Food and Drug Administration (FDA) approved drugs. While researchers have used several general rules of thumb to predict which compounds are likely to benefit from LBDDS, formulation of lipid ...Author: Ronak Savla, Jeff Browne, Vincent Plassat, Kishor M. Wasan, Ellen K. Wasan
http://pharmrev.aspetjournals.org/content/pharmrev/68/3/701.full.pdf
Lipid-Based Drug Delivery Systems in Cancer Therapy: What Is Available and What Is Yet to Come Phatsapong Yingchoncharoen, Danuta S. Kalinowski, and Des R. Richardson Molecular Pharmacology and Pathology Program, Department of Pathology, Faculty of Medicine, Bosch Institute, The University of Sydney, Sydney, NSW, AustraliaAuthor: Phatsapong Yingchoncharoen, Danuta S. Kalinowski, Des R. Richardson
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