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https://www.sciencedirect.com/science/article/pii/0168365996013545
The utility of iontophoresis, the electrically assisted delivery of drugs across the skin, to overcome some of the obstacles of peptide delivery has been widely reported in the literature. Iontophoresis offers similar advantages to passive transdermal delivery in that it is non-invasive and can deliver drugs in a continuous fashion over a prolonged period of time.Author: Philip G. Green
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293348/
Dec 13, 2011 · The iontophoretic delivery of macro-molecules allows the strategy for non-invasive transdermal delivery of peptide-based pharmaceuticals, and contributes to further future advancement toward recombinant DNA technology.
https://www.academia.edu/3300463/Iontophoretic_delivery_of_peptide_drugs
The utility of iontophoresis, the electrically assisted delivery of drugs across the skin, to overcome some of the obstacles of peptide delivery has been widely reported in the literature. Iontophoresis offers similar advantages to passive
https://www.flandershealth.us/therapeutic-peptides/factors-affecting-iontophoretic-delivery.html
May 15, 2019 · 8.4.1.4 Electrode material Appropriate choice of electrodes is a factor that is critical to successful iontophoretic delivery of a drug. The electrode material in an iontophoretic device is very important as it determines the type of electrochemical reaction taking place at the electrodes.
https://www.tandfonline.com/doi/abs/10.1517/17425247.2011.566265
Nov 30, 2017 · (2011). Non-invasive iontophoretic delivery of peptides and proteins across the skin. Expert Opinion on Drug Delivery: Vol. 8, No. 5, pp. 645-663.Author: Taís Gratieri, Dhaval Kalaria, Yogeshvar N Kalia
https://ijpsr.com/bft-article/iontophoresis-controlled-transdermal-drug-delivery-system/?view=fulltext
In that, the iontophoretic technique is one of the most desirable to enhance the transdermal drug delivery of high molecular weight substances like peptide and proteins using a lower current intensity with a short time period for the desired therapeutic effect.
https://www.sciencedirect.com/science/article/pii/S0169409X03002424
A recent in vivo human study by Curdy et al. compared the passive delivery of piroxicam from a gel formulation with the iontophoretic delivery of the drug from an aqueous solution . Three different application times were used, 30, 60 and 125 min, after which the skin was tape-stripped and the drug extracted from the tapes.Author: Yogeshvar N. Kalia, Aarti Naik, James Garrison, Richard H. Guy
https://ijpsr.com/bft-article/iontophoresis-an-approach-to-drug-delivery-enhancement/?view=fulltext
Drug Delivery Pathway in Iontophoresis: Drug delivery indicated the amount of drug present at the site of action at the given time. The penetration of drug will not always be same for everyone as all humans are not the same.
https://www.nature.com/articles/srep26278
May 18, 2016 · Skin, being the largest organ of the body, is an important site for drug administration. However, most of the drugs have poor permeability and thus drug delivery through the skin is very challenging. In this study, we examined the transdermal delivery capability of IMT-P8, a novel cell-penetrating peptide.Author: Ankur Gautam, Jagpreet Singh Nanda, Jesse S. Samuel, Manisha Kumari, Priyanka Priyanka, Gursimran Be...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066337/
Mar 03, 2011 · IONTOPHORESIS MEDIATED TRANSDERMAL DELIVERY OF PROTEINS. Iontophoresis is one of the more successful techniques and has been extensively used for localized drug delivery in physical therapy clinics and is being investigated more recently to enhance transdermal delivery of drugs for systemic administration.Author: Haripriya Kalluri, Ajay K. Banga
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