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https://www.sciencedirect.com/science/article/pii/037851739400323W
The Iontophoretic delivery of the luteinizing hormone releasing hormone (LHRH) analogue, nafarelin ([D-Nal (2) 6 ]LHRH) across hairless mouse skin in vitro has been investigated. The initial range-finding studies showed that a pharmacologically significant amount of the decapeptide can be transported across the skin in a relevant period of time.Author: M.Begoña Delgado-Charro, Richard H. Guy
https://researchportal.bath.ac.uk/en/publications/iontophoretic-delivery-of-nafarelin-across-the-skin
The Iontophoretic delivery of the luteinizing hormone releasing hormone (LHRH) analogue, nafarelin ([D-Nal (2) 6]LHRH) across hairless mouse skin in vitro has been investigated. The initial range-finding studies showed that a pharmacologically significant amount of the decapeptide can be transported across the skin in a relevant period of time.Author: M.Begoña Delgado-Charro, Richard H. Guy
https://core.ac.uk/display/77026758
The Iontophoretic delivery of the luteinizing hormone releasing hormone (LHRH) analogue, nafarelin ([D-Nal (2)6]LHRH) across hairless mouse skin in vitro has been investigated. The initial range-finding studies showed that a pharmacologically significant amount of the decapeptide can be transported across the skin in a relevant period of time.Author: M. Begoña Delgado-Charro and Richard H. Guy
https://www.deepdyve.com/lp/elsevier/iontophoretic-delivery-of-nafarelin-across-the-skin-zM4i31XZBj
The Iontophoretic delivery of the luteinizing hormone releasing hormone (LHRH) analogue, nafarelin ((D-Nal (2) 6 )LHRH) across hairless mouse skin in vitro has been investigated. The initial range-finding studies showed that a pharmacologically significant amount of the decapeptide can be transported across the skin in a relevant period of time.
https://link.springer.com/article/10.1023/A:1016072205371
May 01, 1996 · 1. D. Parasampuria and J. Parasampuria. Percutaneous delivery of proteins and peptides using iontophoretic techniques. J. Clin. Pharm. and Ther. 16:7–17 (1991 ...Author: Amalia M. Rodríguez Bayón, Richard H. Guy
https://www.sciencedirect.com/science/article/pii/S092809870300321X
On the basis of the sample concentrations from the iontophoretic studies, the cumulative amount of drug (μg) transported across the skin was calculated and plotted against time (h). The equation for the linear part of this curve was solved and the slope of the curve (μg h −1 ) was used to calculate the flux value.Author: Johanna Raiman, Maija Koljonen, Katri Huikko, Risto Kostiainen, Jouni Hirvonen
https://www.researchgate.net/publication/8890053_Delivery_and_stability_of_LHRH_and_Nafarelin_in_human_skin_The_effect_of_constantpulsed_iontophoresis
Iontophoresis is a technique used to enhance the transdermal delivery of compounds through the skin via the application of a small electric current. By the process of electromigration and...
https://www.ncbi.nlm.nih.gov/pubmed/26406291
The stratum corneum continues to pose considerable impediment to transdermal drug delivery. One of the effective ways of circumventing this challenge is through the use of iontophoresis. Iontophoresis uses low-level current to drive charged compounds across the skin.Author: Kevin B. Ita
https://www.sciencedirect.com/science/article/pii/S0169409X03002424
Although iontophoresis increased delivery with respect to passive diffusion across intact and impaired rodent skins, the flux across human skin (8.37±2.21 nmol cm −2 h −1) showed only a very modest improvement over passive delivery (1.68±0.34 nmol cm −2 h −1).Author: Yogeshvar N. Kalia, Aarti Naik, James Garrison, Richard H. Guy
https://www.researchgate.net/publication/223473839_Evaluation_of_a_cultured_skin_equivalent_as_a_model_membrane_for_iontophoretic_transport
The Iontophoretic delivery of the luteinizing hormone releasing hormone (LHRH) analogue, nafarelin ([D-Nal (2)6]LHRH) across hairless mouse skin in vitro has been investigated.
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