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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932646/
Jun 24, 2016 · Although not originally purposed for intravesical applications, there is a variety of devices with strong potential for intravesical drug delivery. One example is the devices for intrauterine drug delivery, which also consider ease of insertion, device retention in the …Author: Seung Ho Lee, Young Bin Choy
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664547/
Nov 23, 2015 · Drug-delivery systems (DDSs) have been introduced to control rate, time, and place of release. Drugs can easily reach the bladder through a catheter, while systemically administered agents may undergo extensive metabolism. Continuous urine filling and subsequent washout hinder intravesical drug delivery (IDD).Author: Martino Maria Zacchè, Sushma Srikrishna, Linda Cardozo
https://www.sciencedirect.com/science/article/pii/S0264127516311212
The conventional administration of Mitomycin C (MMC) in intravesical instillations has its limitations. In this study, MMC was loaded onto an in situ forming depot consisting of chitosan (CS), β-glycerophosphate (GP) and Fe 3 O 4 magnetic nanoparticles (Fe 3 O 4-MNPs) to improve its effects.The features and effects of this new drug delivery mode were investigated.Author: Xiaoliang Sun, Peng Sun, Bo Li, Yiqing Liu, Muwen Wang, Ning Suo, Min Yang, Dong Zhang, Xunbo Jin
https://www.sciencedirect.com/science/article/pii/S0378517319302972
This problem can be addressed by intravesical administration of drugs and drug delivery systems via catheter. However, most of intravesical drugs and drug delivery systems are rapidly removed from the bladder during the periodical voiding, meaning that frequent instillations are required with increased risk of bacterial infections and high costs.Author: Noemi Lupo, Aamir Jalil, Imran Nazir, Imran Nazir, Ronald Gust, Andreas Bernkop-Schnürch
https://content.iospress.com/articles/bladder-cancer/blc160056
Jul 27, 2016 · Intravesical drug delivery devices. To increase the dwell time of intravesical drugs, researchers are developing intravesical drug delivery devices that are implanted in the bladder and left in place for an extended period of time. This increases the amount of …Author: Laura Douglass, Mark P. Schoenberg
https://www.suna.org/resources/intravesicalMedAdminStatement.pdf
mixed in a closed system drug transfer device. 3. Alkalization of urine with oral 1.3 gm sodium bicarbonate the night before, morning of and 30 minutes prior to treatment or combination of sodium bicarbonate solution with Mitomycin for intravesical instillation may help improve effectiveness of medication to decrease recurrences of bladder ...
https://www.researchgate.net/publication/305744217_The_Future_of_Intravesical_Drug_Delivery_for_Non-Muscle_Invasive_Bladder_Cancer
The Future of Intravesical Drug Delivery for Non-Muscle Invasive Bladder Cancer: ... This study aimed to develop an intravesical delivery system of gemcitabine HCl for superficial bladder cancer ...
https://www.researchgate.net/publication/307874872_A_new_drug_delivery_system_for_Mitomycin_C_to_improve_intravesical_instillation
[Show full abstract] the liposomes drug delivery system as the stability of the product in biological fluids is the main problem associated with the liposomal drug delivery system. In the present ...
https://www.auanet.org/guidelines/intravesical-administration-of-therapeutic-medication
Intravesical Administration of Therapeutic Medication. ... Intravesical BCG is contraindicated (but not limited to) the following conditions: Within 7 to 14 days of bladder or prostatic surgery, including biopsy; ... Type A or in a closed system drug transfer device.
https://link.springer.com/article/10.2165%2F00003088-199937010-00004
Oct 14, 2012 · Intravesical drug administration is widely used in the treatment of patients with superficial bladder cancer, and aims to optimise drug delivery in the vicinity of …Author: Martin S. Highley, Allan T. van Oosterom, Robert A. Maes, Ernst A. De Bruijn, Ernst A. De Bruijn
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