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https://stm.sciencemag.org/content/scitransmed/10/422/eaam7577.full.pdf
Intravenous delivery of oncolytic reovirus to brain tumor patients immunologically primes for subsequent checkpoint blockade Adel Samson,1* Karen J. Scott,1† David Taggart,1† Emma J. West,1 Erica Wilson,1 Gerard J. Nuovo,2 Simon Thomson,3 Robert Corns,3 Ryan …Author: Adel Samson, Karen J. Scott, David Taggart, Emma J. West, Erica Wilson, Gerard J. Nuovo, Simon Thoms...
https://www.upmc.com/media/news/010120-bcg-iv-vaccine
Researchers at the University of Pittsburgh School of Medicine and the National Institute of Allergy and Infectious Diseases (NIAID) discovered that intravenous TB vaccination is highly protective against the infection in monkeys, compared to the standard injection …
https://www.scholars.northwestern.edu/en/publications/investigation-of-intravenous-delivery-of-nanoliposomal-topotecan-
Here, we demonstrate that intravenous administration of a novel nanoliposomal formulation of TPT (nLS-TPT) extends the survival of mice with intracranial GBM xenografts, relative to administration of free TPT, because of improved biodistribution and pharmacokinetics of the liposome-formulated drug.Author: Laura P. Serwer, Charles O. Noble, Karine Michaud, Daryl C. Drummond, Dmitri B. Kirpotin, Tomoko Oza...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051274/
Jun 10, 2014 · Adeno-associated virus serotype 9 (AAV9)-mediated gene transfer has been reported in central nervous system (CNS) and peripheral tissues. The current study compared the pattern of expression of Green Fluorescent Protein (GFP) across the mouse CNS and selected peripheral tissues after intrathecal (i.t.) or intravenous (i.v.) delivery of equivalent doses of single-stranded AAV9 vector.Author: Daniel J. Schuster, Jaclyn A. Dykstra, Maureen S. Riedl, Kelley F. Kitto, Lalitha R. Belur, R. Scott...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637493/
Jul 17, 2019 · To date, only intravenous thrombolysis (tPA) and mechanical thrombectomy have been shown to be effective in the acute phase of ischemic stroke. However, the narrow therapeutic window (< 4.5 h for tPA and < 6–24 h for endovascular treatment [2, 3]) limits its application to a small percentage of patients. Cell therapy is an interesting and ...Author: Mari Carmen Gómez-de Frutos, Fernando Laso-García, Luke Diekhorst, Laura Otero-Ortega, Blanca Fuente...
https://www.ttp.com/blog/beyond-intravenous-delivery-choosing-better-administration-routes-for-oncologic-drugs
May 13, 2019 · Intravenous delivery remains the dominant paradigm in oncology, but even with precision medicine few drugs pass late stage clinical trials. Karthik Chellappan proposes that early exploration of better administration routes could make all the difference.
https://quizlet.com/45993995/intravenous-delivery-flash-cards/
drug mixed with IV small amount of solution (e.g., 50-100 mL) and administered over short period at prescribed interval, e.g., q4h
https://medical-dictionary.thefreedictionary.com/intravenous
intravenous: [ in″trah-ve´nus ] within a vein. intravenous infusion administration of fluids into a vein by means of a steel needle or plastic catheter. This method of fluid replacement is used most often to maintain fluid and electrolyte balance, or to correct fluid volume deficits after excessive loss of body fluids, in patients unable to ...
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