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https://www.neuromodulation.com/pump
Intrathecal or Intraspinal Drug Delivery (IDD) Overview. In intrathecal drug delivery, pain medications and/or medications used for spasticity are introduced directly to the spinal fluid (intrathecal space) through a drug delivery system comprised of a pump and catheter.
https://www.ncbi.nlm.nih.gov/books/NBK538237/
Apr 30, 2019 · Complications associated with the intrathecal delivery system can subdivide into surgery-related complications and device-related complications. Surgery-related complications generally occur in the perioperative period. Possibly the most worrisome and avertible surgery-related complication is a pump pocket hematoma.Author: Neal Shah, Devang Padalia
https://www.sciencedirect.com/science/article/pii/S0169409X20300120
Intrathecal (IT) administration, i.e., the injection of substances directly into cerebrospinal fluid (CSF) that fills the thecal sac, is a potentially powerful drug delivery approach. This route of administration can achieve a high concentration of therapeutic agent within the central nervous system (CNS) while minimizing off-target exposure ...Author: M.J. Fowler, J.D. Cotter, B.E. Knight, E.M. Sevick-Muraca, D.I. Sandberg, D.I. Sandberg, R.W. Sirian...
https://www.ucsfhealth.org/treatments/intrathecal-drug-delivery
Intrathecal drug delivery, also known as the "pain pump," uses a small pump to deliver pain medication directly to your spinal cord. The pump is surgically placed under the abdominal skin and delivers pain medication through a catheter to the area around your spinal cord.
https://journals.lww.com/anesthesia-analgesia/fulltext/2020/02000/intrathecal_drug_delivery_systems_for_cancer_pain_.6.aspx
The safety and efficacy of intrathecal drug delivery systems (IDDSs) for the treatment of cancer-related pain have been demonstrated in randomized controlled clinical trials (RCTs). Despite positive evidence for this therapy, IDDS remains underutilized to treat cancer pain. Real-world registry data augment existing safety and effectiveness data ...
https://www.medtronic.com/us-en/healthcare-professionals/therapies-procedures/neurological/targeted-drug-delivery.html
Targeted Drug Delivery Healthcare Professionals. CONFIDENT PROGRAMMING ACCOMPLISHED . Medtronic provides the latest in programming technology with the SynchroMed™ II Clinician Programmer featuring visuals, workflow guides, a vibrant backlit screen, and a wireless communicator to help simplify programming.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892916/
Jul 28, 2014 · Intrathecal drug delivery is an effective pain management option for patients with chronic and cancer pain. The delivery of drugs into the intrathecal space provides superior analgesia with smaller doses of analgesics to minimize side effects while significantly improving quality of life.Author: Gaurav Bhatia, Mary E Lau, Katharine M Koury, Padma Gulur
https://www.medtronic.com/us-en/patients/treatments-therapies/drug-pump-chronic-pain.html
Deer T, Chapple I, Classen A, et al. Intrathecal drug delivery for treatment of chronic low back pain; report from the National Outcomes Registry for Low Back Pain. Pain Med. 2004;5(1):6-13. 3
https://www.sciencedirect.com/science/article/pii/S0163725814001041
Intrathecal delivery of protein therapeutics to the brain: A critical reassessment. ... Here, we review blood–brain barrier functions and cerebrospinal fluid dynamics and their relevance to drug delivery via the intrathecal route, discuss animal and human studies that have investigated intrathecal delivery of protein therapeutics, and outline ...Author: Pericles Calias, William A. Banks, David Begley, Maurizio Scarpa, Patricia Dickson
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