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https://www.neuromodulation.com/pump
In intrathecal drug delivery, pain medications and/or medications used for spasticity are introduced directly to the spinal fluid (intrathecal space) through a drug delivery system comprised of a pump and catheter. The intrathecal space is usually accessed from the lumbar region of the lower back.
https://www.ucsfhealth.org/treatments/intrathecal-drug-delivery
Intrathecal drug delivery is used to treat pain from a variety of conditions, such as chronic back and neck pain, sciatica, chronic abdominal pain, failed back and neck surgery, cancer and reflex sympathetic dystrophy or complex regional pain syndrome.
https://www.ncbi.nlm.nih.gov/books/NBK538237/
Apr 30, 2019 · An intrathecal drug delivery system consists of two parts, a pump, and an intrathecal catheter. The pump serves as the drug reservoir, and it is implanted under the subcutaneous tissue in the abdominal area. The second is the catheter which attaches to the pump and delivers medications directly into the intrathecal space.Author: Neal Shah, Devang Padalia
https://www.sciencedirect.com/science/article/pii/S0169409X20300120
Intrathecal (IT) administration, i.e., the injection of substances directly into cerebrospinal fluid (CSF) that fills the thecal sac, is a potentially powerful drug delivery approach. This route of administration can achieve a high concentration of therapeutic agent within the central nervous system (CNS) while minimizing off-target exposure and associated toxicity [ 1 ].Author: M.J. Fowler, J.D. Cotter, B.E. Knight, E.M. Sevick-Muraca, D.I. Sandberg, D.I. Sandberg, R.W. Sirian...
https://www.webmd.com/pain-management/guide/spinal-drug-delivery-systems
Pain relief through spinal drug delivery systems, also called intrathecal drug delivery systems, involves implanting a small pump or using a catheter that delivers medication directly to the spinal cord, where pain signals travel. In many cases, spinal drug delivery systems are used to treat people who have cancer pain.
https://www.ncbi.nlm.nih.gov/pubmed/30706405
Intrathecal Delivery of AAV Vectors in Cynomolgus Macaques for CNS Gene Therapy and Gene Expression Analysis in Microdissected Motor Neurons. Borel F(1), Adams E(2), Mueller C(3)(4).Author: Florie Borel, Eric Adams, Christian Mueller
https://www.drugs.com/cg/intrathecal-analgesia.html
What is intrathecal analgesia (IA)? IA is a type of pain control. It is also called spinal anesthesia. Pain medicine is injected around your spinal cord to control pain from surgery or labor and delivery. IA can also be used to control long-term pain from illnesses, such as cancer.
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