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https://journals.lww.com/co-ophthalmology/Fulltext/2013/01000/Intraocular_lens_as_a_drug_delivery_reservoir.11.aspx
To describe the development and use of intraocular lenses (IOLs) as drug delivery systems and to review the current literature on their application and efficacy. Recent findings Many drugs have been loaded onto IOLs by coating or by attachment in a separate reservoir.
https://onlinelibrary.wiley.com/doi/full/10.1111/aos.13759
The intraocular lens as a drug delivery device for an epidermal growth factor–Receptor inhibitor for prophylaxis of posterior capsule opacificationAuthor: Christian Wertheimer, Alexander Kueres, Jakob Siedlecki, Christian Braun, Stefan Kassumeh, Armin Wol...
https://www.ncbi.nlm.nih.gov/pubmed/29855160
The intraocular lens as a drug delivery device for an epidermal growth factor-Receptor inhibitor for prophylaxis of posterior capsule opacification. Wertheimer C(1), Kueres A(1), Siedlecki J(1), Braun C(2), Kassumeh S(1), Wolf A(1), Mayer W(1), Priglinger C(1), Priglinger S(1), Eibl-Lindner K(1).Author: Christian Wertheimer, Alexander Kueres, Jakob Siedlecki, Christian Braun, Stefan Kassumeh, Armin Wol...
https://onlinelibrary.wiley.com/doi/full/10.1111/j.1755-3768.2008.01419.x
Purpose: To evaluate the effect of an intraocular lens (IOL) coated with dexamethasone on postoperative inflammation after cataract surgery. Methods: Clear lens extraction was performed bilaterally in eight 8‐week‐old rabbits. An uncoated silicone IOL (CeeOn; AMO, Santa Ana, CA, USA) was implanted in one randomly selected eye.Author: Maria Kugelberg, Kayvan Shafiei, Ingeborg Van Der Ploeg, Charlotta Zetterström
https://www.ncbi.nlm.nih.gov/pubmed/30630077
Mar 10, 2019 · Dual drug delivery from intraocular lens material for prophylaxis of endophthalmitis in cataract surgery. Topete A(1), Serro AP(1), Saramago B(2).Author: Ana Topete, A.P. Serro, B. Saramago
https://www.sciencedirect.com/science/article/pii/S0378517318309384
Mar 10, 2019 · Cataract is highly prevalent among old population worldwide and replacement of the opacified crystalline lens by an intraocular lens (IOL) is the safest and the most effective treatment.Author: Ana Topete, A.P. Serro, B. Saramago
https://www.sciencedirect.com/science/article/pii/S0886335006008716
In a previous pilot study, 8 we suggested that a hydrophilic acrylic intraocular lens (IOL) (C-flex, Rayner Intraocular Lenses, Ltd.) could serve as a drug-delivery system for fourth-generation fluoroquinolones. In the current study, we present the results of a full-scale evaluation of the ability and safety of the same hydrophilic acrylic IOL as a drug-delivery system for commercially available gatifloxacin and …Author: Guy Kleinmann, David J. Apple, Jesse Chew, Brian Hunter, Scott Stevens, Scott Larson, Nick Mamalis, ...
http://www.mavery.com/academic/Intraocular_DDS.pdf
What is an intraocular drug delivery system? An intraocular drug deliver system (DDS) refers to a device that is surgically implanted into your eye and then ideally would constantly releases drugs for a set time. This includes both biodegradable and non-biodegradable devices, and the development of
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306122/
Dec 26, 2010 · Intraocular or periocular injections can deliver relatively high doses of drug to the eye with few or no systemic side effects. However, such injections are associated with significant complications and must often be repeated at regular intervals. Compliance with any form of regular medication can be a problem,...Author: Nahid Haghjou, Masoud Soheilian, Mohammad Jafar Abdekhodaie
https://www.webmd.com/eye-health/cataracts/intraocular-lens-implant
Intraocular lens (IOL) implants are artificial lenses that help clear up your vision after cataract surgery. Learn about the procedure, its risks, and recovery time.
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