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https://www.sciencedirect.com/science/article/pii/S0169409X0500164X
Dec 13, 2005 · Intraocular sustained drug delivery using implantable polymeric devices ... Possible barriers to intraocular drug delivery. The cornea, tear drainage, and intraocular convection limit the influx of locally administered drugs into the posterior ocular segment. Macromolecules as large as antibodies are unlikely to penetrate the internal limiting ...Author: Tsutomu Yasukawa, Yuichiro Ogura, Eiji Sakurai, Yasuhiko Tabata, Hideya Kimura
https://www.researchgate.net/publication/7504368_Intraocular_sustained_drug_delivery_using_implantable_polymeric_devices
Intraocular sustained drug delivery using implantable polymeric devices Article · Literature Review (PDF Available) in Advanced Drug Delivery Reviews 57(14):2033-46 · January 2006 with 281 Reads
https://www.sciencedirect.com/science/article/abs/pii/S0169409X0500164X
Intraocular sustained drug delivery using implantable polymeric devices ... Intraocular sustained drug release using implantable devices has been investigated to treat vitreoretinal diseases. Possible targeted diseases include those in which repeated intraocular injections are effective (cytomegalovirus retinitis, uveitis), diseases requiring ...Author: Tsutomu Yasukawa, Yuichiro Ogura, Eiji Sakurai, Yasuhiko Tabata, Hideya Kimura
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306122/
Dec 26, 2010 · To overcome the above mentione d limitations, an increasing number of sustained-release drug delivery devices using different mechanisms and containing a variety of agents have been developed to treat uveitis. This article reviews major drug delivery technologies currently in clinical trials or at experimental stages for treatment of uveitis.Author: Nahid Haghjou, Masoud Soheilian, Mohammad Jafar Abdekhodaie
https://www.deepdyve.com/lp/elsevier/intraocular-sustained-drug-delivery-using-implantable-polymeric-0A0AmzQuoP
Dec 13, 2005 · Read "Intraocular sustained drug delivery using implantable polymeric devices, Advanced Drug Delivery Reviews" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401754/
Dec 12, 2018 · The market for polymeric implantable drug delivery devices is one that is growing. The advantages that this delivery route demonstrate over more conventional drug delivery methods, such as oral tablets, make it likely that it will continue to grow and that the number of implantable drug delivery devices on the market will increase.Author: Sarah A. Stewart, Juan Domínguez-Robles, Ryan F. Donnelly, Eneko Larrañeta
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502010000300024
Brazilian Journal of Pharmaceutical Sciences ... focusing on the use of intraocular devices containing different antimetabolites that are able to inhibit the cellular proliferation mechanism. ... SAKURAI, E.; TABATA, Y.; KIMURA, H. Intraocular sustained drug delivery …
https://www.hindawi.com/journals/jdd/2013/895013/
In this regard, implantable delivery systems may relieve the burden of chronic drug administration while potentially ensuring high intraocular drug bioavailability. Presently there are no FDA-approved implantable drug delivery devices for glaucoma even though there are several ongoing clinical studies.Author: Dharani Manickavasagam, Moses O. Oyewumi
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