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https://journals.lww.com/co-ophthalmology/Pages/articleviewer.aspx?year=2013&issue=01000&article=00011&type=Fulltext
Purpose of review To describe the development and use of intraocular lenses (IOLs) as drug delivery systems and to review the current literature on their application and efficacy.. Recent findings Many drugs have been loaded onto IOLs by coating or by attachment in a separate reservoir.
https://www.researchgate.net/publication/232320445_Intraocular_lens_as_a_drug_delivery_reservoir
Intraocular lens as a drug delivery reservoir. ... To describe the development and use of intraocular lenses (IOLs) as drug delivery systems and to review the current literature on their ...
https://insights.ovid.com/ophthalmology/cooph/2013/01/000/intraocular-lens-drug-delivery-reservoir/11/00055735
Purpose of reviewTo describe the development and use of intraocular lenses (IOLs) as drug delivery systems and to review the current literature on their application and efficacy.Recent findingsMany drugs have been loaded onto IOLs by coating or by attachment in a separate reservoir. With incorporatiAuthor: Yu-Chi Liu, Tina T. Wong, Jodhbir S. Mehta
https://www.assignmentpoint.com/science/medical/intraocular-implants-for-extended-drug-delivery.html
Ocular Implants for Drug Delivery. Advances in materials science, biomedical engineering, and surgical techniques have encouraged the development of a variety of intraocular therapeutic devices. One class of intraocular devices includes implants for drug delivery, designed to improve the ability to deliver therapeutic drug levels into the eye.
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502010000300024
Intraocular implants are controlled drug delivery systems prepared from biodegradable or non-biodegradable polymers. Generally, these are introduced into the vitreous through an incision in the ocular pars plana , which is located posterior to the lens and anterior to the retina.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430809/
This review covers reservoir-based drug delivery systems that incorporate microtechnology, with an emphasis on oral, dermal, and implantable systems. Key features of each technology are highlighted such as working principles, fabrication methods, dimensional constraints, and performance criteria.Author: Cynthia L. Stevenson, John T. Santini, Robert Langer
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306122/
Dec 26, 2010 · To overcome the above mentione d limitations, an increasing number of sustained-release drug delivery devices using different mechanisms and containing a variety of agents have been developed to treat uveitis. This article reviews major drug delivery technologies currently in clinical trials or at experimental stages for treatment of uveitis.Author: Nahid Haghjou, Masoud Soheilian, Mohammad Jafar Abdekhodaie
https://patents.google.com/patent/WO2002100318A3/en
A delivery device that allows for the sustained release of an agent, particularly useful for the sustained release of a therapeutic agent to limited access regions, such as the posterior chamber of the eye and inner ear. The delivery device is minimally invasive, refillable and may be easily fixed to the treatment area. The delivery device includes a hollow body with an inlet port at its ...Author: Signe Erickson Varner, Eugene Dejuan, Aaron Christopher Barnes, Terry Harrison Shelley, Michael J. C...
https://patents.google.com/patent/US8663194B2/en
In one aspect, for example, an ocular active agent delivery device ( 10 ) can include an active agent reservoir ( 14 ) disposed in an annular housing ( 12 ), the annular housing ( 12 ) being configured to fit inside of a lens capsule and at least partially encircling a …Author: Balamurali K. Ambati, Bruce K. Gale
https://onlinelibrary.wiley.com/doi/full/10.1111/aos.13759
For testing IOL as a drug delivery device in this setting, an anterior segment model was chosen that imitates the intraocular situation (Gotoh et al. 2007): the membrane acts as the posterior capsule, and cell differentiation, migration, and growth patterns can be monitored from the periphery to the centre of the capsular bag below the modified ...Author: Christian Wertheimer, Alexander Kueres, Jakob Siedlecki, Christian Braun, Stefan Kassumeh, Armin Wol...
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