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http://intranasal.net/Peer%20Reviewed%20literature/Goldman,%20IN%20Drug%20Delivery%20in%20children,%20Curr%20Drug%20therapy%202006.pdf
The current review summarizes available information on the use of intranasal drug delivery for children in acute illness. Midazolam (Versed), Fentanyl, Diamorphine and Ketamine are discussed, as well as pitfalls and caveats of intranasal drug use. INTRODUCTION Significant …
https://www.researchgate.net/publication/228345937_Intranasal_Drug_Delivery_for_Children_with_Acute_Illness
Drug delivery via the nose may be a useful route of adminis- tration for children. The nasal mucosa is richly vascularised which provides fast and direct access to the systemic circulation and may ...
http://www.eurekaselect.com/55161
The current review summarizes available information on the use of intranasal drug delivery for children in acute illness. Midazolam (Versed), Fentanyl, Diamorphine and Ketamine are discussed, as well as pitfalls and caveats of intranasal drug use.Author: Ran D. Goldman
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544782/
Oct 10, 2014 · Pain is the most common symptom in the emergency setting; however, timely management of acute pain in children continues to be suboptimal. Intranasal drug delivery has emerged as an alternative method of achieving quicker drug delivery without adding to the distress of a child by inserting an intravenous cannula.Author: Adrian Murphy, Ronan O'Sullivan, Abel Wakai, Timothy S Grant, Michael J Barrett, John Cronin, Siobha...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716920/
Jul 10, 2013 · The intranasal (IN) delivery of analgesic agents provides quick and simple drug administration without the need for needles , a particular advantage in pediatric patients. Intranasal delivery of fentanyl is a widely accepted pain relief strategy in children both in …Author: Andis Graudins, Andis Graudins, Robert Meek, Diana Egerton-Warburton, Diana Egerton-Warburton, Rober...
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.551.8682
The nose has a very rich vascular supply, it facilitates direct absorption to the systemic blood supply and increases bioavailability of the drug, compared to oral administration. The current review summarizes available information on the use of intranasal drug delivery for children in acute illness.
https://www.cochrane.org/CD009942/ANAESTH_intranasal-fentanyl-treatment-children-acute-pain
Oct 10, 2014 · Pain is the most common symptom in the emergency setting; however, timely management of acute pain in children continues to be suboptimal. Intranasal drug delivery has emerged as an alternative method of achieving quicker drug delivery without adding to the distress of a child by inserting an intravenous cannula.
https://clinicaltrials.gov/ct2/show/NCT02388321
Mar 17, 2015 · Intranasal (IN) delivery of analgesic agents provides rapid and convenient drug administration without the need for needles. In children, the placement of an intravenous line often increases anxiety and pain, requires nursing time, and can be very difficult to achieve, so the IN route is particularly advantageous.
https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD009942.pub2/abstract
Oct 10, 2014 · Pain is the most common symptom in the emergency setting; however, timely management of acute pain in children continues to be suboptimal. Intranasal drug delivery has emerged as an alternative method of achieving quicker drug delivery without adding to the distress of a child by inserting an intravenous cannula. ObjectivesAuthor: Adrian Murphy, Ronan O'Sullivan, Abel Wakai, Timothy S Grant, Michael J Barrett, John Cronin, Siobha...
https://www.ommegaonline.org/article-details/Intranasal-ketamine-as-analgesia-to-treat-refractory-pain-in-children-in-the-outpatient-setting/1230
Ketamine has become a useful analgesic in treating neuropathies, disorders of central sensitization, and hyperalgesia in adults and children. It has been delivered by various routes including intravenous, oral, sublingual, topical, rectal, intramuscular, intrathecal, and intranasal with documented success in the inpatient and acute care settings.Author: Elizabeth Bettini, David Steinhorn, Deborah Lafond, Ommega Internationals
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