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https://www.ncbi.nlm.nih.gov/pubmed/21417782/
EXPERT OPINION: Intranasal delivery of stem cells is a new method with great potential for the transplantation of stem cells into the brain, and it may provide an extraordinary approach to overcoming the existing barriers of stem cell delivery for the treatment of many neurological disorders.Author: Yongjun Jiang, Juehua Zhu, Gelin Xu, Xinfeng Liu
https://www.ncbi.nlm.nih.gov/pubmed/19324456
Intranasal delivery of cells to the brain. Danielyan L(1), Schäfer R, von Ameln-Mayerhofer A, Buadze M, Geisler J, Klopfer T, Burkhardt U, Proksch B, Verleysdonk S, Ayturan M, …Author: Lusine Danielyan, Richard Schäfer, Andreas von Ameln-Mayerhofer, Marine Buadze, Julia Geisler, Tim K...
https://journals.lww.com/neurotodayonline/pages/articleviewer.aspx?year=2009&issue=08030&article=00002&type=Fulltext
They thought this might help the stem cells migrate better into the brain. In both cases, the stem cells reached the brain within one hour. When hyaluronidase was used, twice the number of stem cells made it into the brain. “We see these stem cells in the olfactory bulb, thalamus, hippocampus, and in the cortex,” Dr. Frey explained.
https://www.sciencedirect.com/science/article/pii/S0171933509000211
In the present study, the IN delivery of mesenchymal stem cells and glioma cells to the brain demonstrates that cells applied intranasally can migrate to the intact brain through the cribriform plate along the olfactory neural pathway and possibly along other routes of migration.Author: Lusine Danielyan, Richard Schäfer, Andreas von Ameln-Mayerhofer, Marine Buadze, Julia Geisler, Tim K...
https://stemedix.com/intranasal-delivery-of-stem-cells
Mar 21, 2016 · Though research has shown that stem cells are therapeutic candidates for neurodegenerative diseases like Parkinson’s disease, scientists have been working on overcoming the challenges associated with effectively delivering these cells to the brain. A recent study, published in the journal Rejuvenation Research, demonstrated that intranasal delivery of stem cells provided both …
https://www.jove.com/video/55845/intranasal-delivery-therapeutic-stem-cells-to-glioblastoma-mouse
Stem cells are promising therapeutic carriers to treat brain tumors due to their intrinsic tumor tropism. Non-invasive intranasal stem cell delivery bypasses the blood brain barrier and demonstrates strong potential for clinical translation. …Author: Dou Yu, Gina Li, Maciej S. Lesniak, Irina V. Balyasnikova
https://www.tandfonline.com/doi/abs/10.1517/17425247.2011.566267
Jun 19, 2013 · Expert opinion: Intranasal delivery of stem cells is a new method with great potential for the transplantation of stem cells into the brain, and it may provide an extraordinary approach to overcoming the existing barriers of stem cell delivery for the treatment of many neurological disorders. This potential benefit emphasizes the importance of ...Author: Yongjun Jiang, Juehua Zhu, Gelin Xu, Xinfeng Liu
https://journals.sagepub.com/doi/full/10.3727/096368914X684970
Our previously published work demonstrated that noninvasive intranasal application (INA) of bone marrow-derived MSCs results in delivery of numerous stem cells to different brain areas of healthy rodents and of the rat 6-OHDA model of PD, including the …
https://www.youtube.com/watch?v=YcIi-B2Mtko
Apr 26, 2019 · Dr. Centeno discusses intra-nasal delivery of stem cells. This means that the doctor wants to put stem cells up your nose to treat your brain. Is this a thing?Author: Chris Centeno, M.D.
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