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https://www.westpharma.com/products/intradermal-delivery
Intradermal Delivery An easy and reliable solution for intradermal injection The ID Adapter is a novel injection guide designed for use with 1mL 1/2 inch fixed needle allergy syringes.
https://www.nanopass.com/technology/
Patented Technology. Hollow microneedles for intradermal injection. Intradermal delivery. Intradermal vaccine delivery has been repeatedly shown to allow significant dose sparing when compared to conventional administration methods such as intramuscular and subcutaneous administration. The dermis and epidermis of the human skin are rich in ...
https://www.nature.com/articles/s41467-019-08852-4
Feb 20, 2019 · Intradermal VEGF-A mRNA was well tolerated and led to local functional VEGF-A protein expression and transient skin blood flow enhancement in men with T2DM. ... Intradermal delivery of …Author: Li-Ming Gan, Li-Ming Gan, Li-Ming Gan, Maria Lagerström-Fermér, Leif G. Carlsson, Cecilia Arfvidsson...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898465/
Design and evaluate a new micro-machining based approach for fabricating dissolvable microneedle arrays (MNAs) with diverse geometries and from different materials for dry delivery to skin microenvironments. The aims are to describe the new fabrication ...Author: Bekir Bediz, Emrullah Korkmaz, Rakesh Khilwani, Cara Donahue, Geza Erdos, Louis D. Falo, O. Burak Oz...
https://path.azureedge.net/media/documents/TS_opt_idd_review.pdf
Intradermal Delivery of Vaccines Executive summary The dermis and epidermis of the human skin are rich in antigen-presenting cells. It has been proposed that delivery of vaccine antigens to these tissues (i.e., intradermal delivery) rather than to muscle or subcutaneous tissue could therefore induce superior protective immune
https://www.sciencedirect.com/science/article/pii/S1742706115002846
To quantitatively evaluate the intradermal delivery of anti-TNF-α Ab and kinetics of the intradermal delivery from tip-loaded CMC-MNAs to ex vivo human skin, tip-loaded CMC-MNAs with embedded Cy3-labeled anti-TNF-α Ab were prepared through the spin-casting technique as described above. Subsequently, MNAs were applied to human skin explants in ...Author: Emrullah Korkmaz, Emily E. Friedrich, Mohamed H. Ramadan, Geza Erdos, Alicia R. Mathers, O. Burak Oz...
https://drug-dev.com/intradermal-delivery-new-technology-brings-simplicity-scalability-to-intradermal-drug-delivery/
Intradermal drug delivery is increasingly recognized as a potential solution to many of the challenges faced by new and existing medicines. Intradermal dosing provides the opportunity to more effectively administer agents such as small molecules, biologics, and vaccines, allowing for improved bioavailability.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044245/
Mar 01, 2011 · Delivery of vaccine antigens to the dermis and/or epidermis of human skin (i.e. intradermal delivery) might be more efficient than injection into the muscle or subcutaneous tissue, thereby reducing the volumes of antigen. This is known as dose-sparing ...Author: JK Hickling, KR Jones, M Friede, D Zehrung, D Chen, D Kristensen
https://drug-dev.com/intradermal-delivery-advances-in-intradermal-drug-delivery/
Intradermal delivery of DNA vaccines combined with electrophoresis have been shown to enhance delivery.3 For researchers conducting clinical trials using Mantoux ID injection, there is the additional question of whether the lack of efficacy is due to the vaccine or the injection technique.
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