We have collected information about Intraarticular Drug Delivery In Osteoarthritis for you. Follow the links to find out details on Intraarticular Drug Delivery In Osteoarthritis.
https://www.sciencedirect.com/science/article/pii/S0169409X06000160
Intraarticular drug delivery in osteoarthritis ... Osteoarthritis (OA) is a primarily non-inflammatory, degenerative joint disease characterized by progressive loss of articular cartilage, subchondral bone sclerosis, osteophyte formation, changes in the synovial membrane, and an increased volume of synovial fluid with reduced viscosity and ...Author: Nicole Gerwin, Caroline Hops, Andrea Lucke
https://www.sciencedirect.com/science/article/pii/S1359644618300461
Schematic representation of the retention time and clearance of various biodegradable osteoarthritis (OA) drug delivery systems (DDSs) after intra-articular (IA) administration. Free drugs, hydrogel, nanoparticles and microparticles remain in the joint for hours, days, weeks and months, respectively.Author: Pierre Maudens, Olivier Jordan, Eric Allémann
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015522/
Introduction. Intra-articular (IA) drug delivery presents many advantages as it offers direct access to the joint space, thus increasing the bioavailability of therapeutic agents at the affected site while reducing systemic exposure, potential side effects and overall cost.Author: Muhammad Farooq Rai, Christine T.N. Pham
https://www.ncbi.nlm.nih.gov/pubmed/29792929
To satisfy this unmet medical need, drug delivery systems (DDSs) containing disease-modifying OA drugs (DMOADs) for intra-articular (IA) administration are required to improve the health of OA patients. DDSs should provide controlled and/or sustained drug release, enabling long-term treatment with a reduced number of injections.Author: Pierre Maudens, Olivier Jordan, Eric Allémann
https://www.nature.com/articles/s41584-018-0123-4
Nov 29, 2018 · Intra-articular drug delivery has a number of advantages over systemic administration; however, for the past 20 years, intra-articular treatment options for …Author: Ian A. Jones, Ryan Togashi, Melissa L. Wilson, Nathanael Heckmann, C. Thomas Vangsness
https://www.hindawi.com/journals/jnt/2012/748909/
The objective of this paper is to provide readers with current developments of intra-articular drug delivery systems. In recent years, although the search for a clinically successful ideal carrier is ongoing, sustained-release systems, such as polymeric micro- and nanoparticles, liposomes, and hydrogels, are being extensively studied for intra-articular drug delivery purposes. The advantages ...Author: Zhiyue Zhang, Guihua Huang
https://www.researchgate.net/publication/7205668_Intra-articular_drug_delivery_in_osteoarthritis_Adv
Intra-articular drug delivery has a number of advantages over systemic administration; however, for the past 20 years, intra-articular treatment options for the management of knee osteoarthritis ...
https://www.deepdyve.com/lp/elsevier/intraarticular-drug-delivery-in-osteoarthritis-aP0Q0kluq0
May 20, 2006 · Intraarticular drug delivery in osteoarthritis Intraarticular drug delivery in osteoarthritis Gerwin, Nicole; Hops, Caroline; Lucke, Andrea 2006-05-20 00:00:00 Osteoarthritis (OA) is a primarily non-inflammatory, degenerative joint disease characterized by progressive loss of articular cartilage, subchondral bone sclerosis, osteophyte formation, changes in the synovial membrane, and an ...
https://www.researchgate.net/publication/264502552_Progress_in_Intra-Articular_Drug_Delivery_Systems_for_Osteoarthritis
To guarantee the efficacy and avoid frequent injections, rationally designed intra-articular drug delivery systems (DDSs), which may remain in OA joints for a long time and sustainedly release ...
https://www.tandfonline.com/doi/abs/10.1517/17425247.2014.867325
Jan 09, 2009 · Introduction: Intra-articular (IA) drug delivery is very useful in the treatment of osteoarthritis (OA), the most common chronic joint affliction. However, the therapeutic effect of IA administration depends mostly on the efficacy of drug delivery. Areas covered: The present article reviews the current status of IA therapy for OA treatment as well as its rationale.Author: Mi Lan Kang, Gun-Il Im
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