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https://www.researchgate.net/publication/7471431_Intelligent_hydrogels_for_the_oral_delivery_of_chemotherapeutics
Intelligent hydrogels for the oral delivery of chemotherapeutics Article · Literature Review in Expert Opinion on Drug Delivery 2(6):1003-13 · December 2005 with 18 Reads How we measure 'reads'Author: Lev Bromberg
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549393/
Areas covered. This review provides a wide perspective on the therapeutic use of hydrogels in oral delivery systems. General features and advantages of hydrogels are addressed, with more considerable focus on stimuli-responsive systems that respond to pH or enzymatic changes in the gastrointestinal environment to achieve controlled drug release.Author: Lindsey A Sharpe, Adam M Daily, Sarena D Horava, Nicholas A Peppas
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.391.9329
CiteSeerX - Document Details (Isaac Councill, Lee Giles, Pradeep Teregowda): Chemotherapy and the use of chemotherapeutic agents have become routine in first line defense in the battle against cancer. In its current state, chemotherapy has only advanced in terms of new drugs and modifying existing drugs, but there is still a need for improved delivery methods, particularly oral delivery.
https://pubs.acs.org/doi/abs/10.1021/ie1008025
Complexation Hydrogels as Oral Delivery Vehicles of Therapeutic Antibodies: An in Vitro and ex Vivo Evaluation of Antibody Stability and Bioactivity. ... Intelligent recognitive systems in nanomedicine. ... pH-responsive hydrogels with dispersed hydrophobic nanoparticles for the oral delivery of chemotherapeutics.Author: Daniel A. Carr, Marta Gómez-Burgaz, Mathilde C. Boudes, Nicholas A. Peppas
https://www.tandfonline.com/doi/abs/10.1517/17425247.2014.902047
Jul 21, 2014 · Introduction: Oral delivery of therapeutics, particularly protein-based pharmaceutics, is of great interest for safe and controlled drug delivery for patients. Hydrogels offer excellent potential as oral therapeutic systems due to inherent biocompatibility, diversity of both natural and synthetic material options and tunable properties.Author: Lindsey A Sharpe, Adam M Daily, Sarena D Horava, Nicholas A Peppas
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195952/
Oct 30, 2011 · For example, the pH-dependent complexation behavior of each of these hydrogels was studied for either oral delivery or intracellular delivery. Hydrogels which undergo a sharp swelling transition at different pHs are highly advantageous for both oral delivery and intracellular delivery.Author: William B. Liechty, Mary Caldorera-Moore, Margaret A. Phillips, Cody Schoener, Nicholas A. Peppas
http://biomat.bme.utexas.edu/pubs/index.htm
Betancourt, J. Prado, K. Soo and N.A. Peppas, “Characterization of pH-Responsive Hydrogels of Poly(itaconic acid)-g-Poly(ethylene glycol) Prepared by UV-Initiated Free Radical Polymerization as Biomaterials for Oral Delivery of Biological Compounds”, J. Biomed.
https://pubs.acs.org/doi/pdf/10.1021/acsbiomaterials.8b00348
delivery profiles may be therapeutically beneficial and suggest that magnetically responsive hydrogels could provide useful tools for optimizing and clinically deploying pulsatile chemotherapeutic delivery profiles. KEYWORDS: chemotherapy, cancer therapy, responsive hydrogels, smart hydrogels, ferrogels, on-demand drug delivery 1. INTRODUCTION
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