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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086619/
However, the investigation of integrin αvβ3 targeted delivery of radiotherapeutics is relatively rare. Integrin targeted radionuclide therapy is considered to specifically deliver radiation to the tumor cells or tumor vasculature, thereafter leading to the death of tumor cells and the inhibition of tumor growth.Author: Zhaofei Liu, Fan Wang, Xiaoyuan Chen
https://www.researchgate.net/publication/51102697_Integrin_Targeted_Delivery_of_Radiotherapeutics
In this article we will review the role of integrin alpha(v)beta(3) in angiogenesis, present recent progress in the use of integrin alpha(v)beta(3) antagonists and integrin-targeted delivery ...
https://www.thno.org/v01p0201.pdf
a suitable maker for cancer-targeted drug delivery [5, 12]. Several delivery vehicles such as antibodies, RGD peptides, peptidomimetics, and other small molecules have been investigated for integrin targeted delivery of chemical drugs, cytotoxicities and gene inhibitors …
https://www.thno.org/v01p0201.htm
However, the investigation of integrin αvβ3 targeted delivery of radiotherapeutics is relatively rare. Integrin targeted radionuclide therapy is considered to specifically deliver radiation to the tumor cells or tumor vasculature, thereafter leading to the death of tumor cells and the inhibition of tumor growth.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086622/
Integrin targeted delivery of nanoparticle-carried chemotherapeutic agents. The third approach is to employ a nanoparticle-carried delivery system. Integrin targeted ligands, such as RGD peptides, can be coated on the surface of nanoparticle carrier system to selectively deliver chemotherapeutic agents to cancer cells or diseased tissues.Author: Zhaofei Liu, Fan Wang, Xiaoyuan Chen
https://core.ac.uk/display/8559376
Abstract. Targeted radionuclide therapy, which is based on the selective delivery of a sufficient radiation dose to tumors without significantly affecting normal tissues, is a promising therapeutic approach for the treatment of a wide variety of malignancies.Author: Zhaofei Liu, Fan Wang and Xiaoyuan Chen
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.291.9001
BibTeX @MISC{Liu11reviewintegrin, author = {Zhaofei Liu and Fan Wang and Xiaoyuan Chen}, title = {Review Integrin Targeted Delivery of Radiotherapeutics}, year = {2011}}
http://europepmc.org/articles/PMC3075613
Jan 01, 2011 · This theme collection of articles first introduces integrin biology followed by integrin targeted imaging and therapy applications. ... Wang F, Chen X. Integrin targeted delivery of radiotherapeutics. Theranostics. 2011; 1:201–210. [PMC free article] 12. Juliano RL, Ming X, Nakagawa O, Xu R, Yoo H. Integrin targeted delivery of gene ...Author: Xiaoyuan Chen
https://pubs.rsc.org/en/content/articlelanding/2015/dt/c4dt02710h
Conjugates of a Pt(iv) derivative of picoplatin with monomeric (Pt–c(RGDfK), 5) and tetrameric (Pt–RAFT-{c(RGDfK)}4, 6) RGD-containing peptides were synthesized with the aim of exploiting their selectivity and high affinity for αVβ3 and αVβ5 integrins for targeted delivery of this anticancer metallodrug to tAuthor: Anna Massaguer, Alejandro González-Cantó, Esther Escribano, Silvia Barrabés, Gerard Artigas, Virtude...
https://www.researchgate.net/publication/10924836_Integrin-mediated_targeting_of_drug_delivery_to_irradiated_tumor_blood_vessels
Integrin-mediated targeting of drug delivery to irradiated tumor blood vessels ... Radiation-guided drug delivery to tumor blood vessels is a novel paradigm for targeted drug delivery ...
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