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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787057/
Continuous subcutaneous insulin infusion. More physiologic delivery of insulin has been a long-standing goal. In normal physiology, a continuous small amount of insulin secretion from the beta cells of the pancreas reduces hepatic glucose output, and a larger amount of insulin is secreted when food is ingested to maintain euglycemia.[] Although multiple daily injections (MDI) therapy can ...
https://medicalxpress.com/news/2020-04-toss-syringe-oral-delivery-drugs.html
1 day ago · Intestine-specific delivery of insulin demonstrates promise with new oral formulation Oct 27, 2015 Fatty acid in triglycerides proves an effective platform for biological drug delivery
https://link.springer.com/chapter/10.1007/0-306-46803-4_13
Human Insulin Insulin Analog Continuous Subcutaneous Insulin Infusion Regular Insulin Insulin Delivery These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.Author: Jens Brange, Lotte Langkjær
https://www.researchgate.net/publication/226731995_Insulin_Formulation_and_Delivery
Insulin Formulation and Delivery. ... Despite numerous efforts over the past few decades to develop insulin delivery systems, there is still no commercially available oral insulin. The reasons why ...
https://www.sciencedirect.com/science/article/pii/S0168365917308283
4. Barriers to oral delivery of insulin nanoparticle formulation. Effective oral delivery of insulin remains a significant challenge due to a few physiological barriers. The major barriers to oral administration of insulin can be classified as physical, chemical and enzymatic.Author: Chun Y. Wong, Hani Al-Salami, Crispin R. Dass
https://www.researchgate.net/publication/281970332_Formulation_of_Powder_Dosage_Form_of_Insulin_for_Intranasal_Delivery
Formulation of Powder Dosage Form of Insulin for Intranasal Delivery. ... 30 and 15% in blood glucose level for formulation E and 40 and 30% for formulation H as against the subcutaneously ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787047/
Hepatic-directed vesicle insulin (HDV-I) is a novel investigational (<150 nm diameter) insulin delivery system developed by Diasome Pharmaceuticals, Inc. 5–9 It is formulated for subcutaneous (SC) and oral gel cap administration. The SC HDV-I formulation contains 1% bound insulin and 99% untargeted free insulin.
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