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https://www.cardiosmart.org/healthwise/hw22/2014/hw222014
For short-term treatment of preterm labor. Before 31 to 32 weeks of pregnancy. Indomethacin can be used to treat preterm labor when: Labor needs to be delayed for 24 to 48 hours to: Let corticosteroids given to the mother help fetal lungs mature.
https://www.uptodate.com/contents/inhibition-of-acute-preterm-labor
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https://www.drugs.com/pregnancy/indomethacin.html
Jan 13, 2020 · Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include IBM Watson Micromedex (updated 28 Feb 2020), Cerner Multum™ (updated 2 Mar 2020), …7.8/10
http://www.gyncph.dk/procedur/ref/obstet/indometacin%202012.pdf
was no difference with respect to delivery rate 48 hours after treatment, gestational age at delivery, birth weight, and neonatal morbidity and deaths. Zuckerman et al,23 in a prospective, randomized, double-blind study, examined the effect of 200 to 300 mg indometh-acin in women with PTL between 24 and 34 weeks of gestation.
https://clinicaltrials.gov/ct2/show/NCT00486824
Jun 15, 2007 · Indomethacin Versus Nifedipine for Preterm Labor Tocolysis. ... An abdominal ultrasound will be performed in the labor and delivery unit prior to the administration of the tocolytic in order to assess fetal position and fluid level, and to document fetal cardiac activity and movement, and will be repeated at 48 hours post-randomization ...
https://www.rxlist.com/indocin-drug.htm
Mar 09, 2020 · Labor or Delivery. There are no studies on the effects of INDOCIN during labor or delivery. In animal studies, NSAIDs, including indomethacin, inhibit prostaglandin synthesis, cause delayed parturition, and increase the incidence of stillbirth. Data. Animal data
https://www.nejm.org/doi/full/10.1056/NEJM198808113190602
Abstract Indomethacin is a potent agent in the treatment of premature labor, but its use has been limited because of concern about its constrictive effects on the fetal ductus arteriosus. To study ...Author: Kenneth J. Moise, James C. Huhta, Dawod S. Sharif, Ching-Nan Ou, Brian Kirshon, Nathan Wasserstrum, ...
https://www.ncbi.nlm.nih.gov/pubmed/21786219/
Preterm labor (PTL) is a major cause of neonatal morbidity and mortality worldwide. Among the available tocolytics, indomethacin, a prostaglandin synthetase inhibitor, has been in use since the 1970s. Recent studies have suggested that prostaglandin synthetase inhibitors are superior to other tocolytics in delaying delivery for 48 hours and 7 days.Author: Gael Abou-Ghannam, Ihab M. Usta, Anwar H. Nassar
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