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http://digitallibrary.usc.edu/cdm/ref/collection/p15799coll127/id/562157
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576846/
The simplest miniaturized implantable drug-delivery systems feature a reservoir with a membrane that controls the onset or rate of drug administration. Reservoir-based drug-delivery systems may require additional energy to overcome the diffusion limited transport of drug in …Author: Ellis Meng, Tuan Hoang
https://www.pharmatutor.org/articles/review-implantable-drug-delivery-system
Therefore, drug delivery systems were developed to optimize the therapeutic properties of drug products and render them more safe, effective, and reliable. In comparison with many of the other drug delivery systems, implantable pumps and implants for variable rate delivery are at a crude stage of development.
https://www.slideshare.net/pareshbharodiya/implantable-drug-delivery-system
May 13, 2010 · various approaches to design implantable drug delivery system. various approaches to design implantable drug delivery system. ... Implantable drug delivery systeman introduction <br />Implantable drug delivery systems are placed completely under the skin — usually in a convenient but inconspicuous location. The patient is aware of only a ...
https://www.sciencedirect.com/science/article/pii/S1359028602000323
The BioMEMS field is rapidly advancing as new applications and devices are studied. BioMEMS have the potential to enhance the way medicine is practiced and improve patient health. The use of BioMEMS for drug delivery, through biocapsules, microneedles, micropumps, and microreservoir devices, has the potential to improve drug therapy.Author: Rebecca S Shawgo, Amy C Richards Grayson, Yawen Li, Michael J Cima
https://www.sciencedirect.com/science/article/pii/B9780128136652000132
The concept of implantable drug delivery systems (IDDSs) in modern medicine may be traced to Deansby and Parkes who, in 1938, subcutaneously (SC) implanted compressed pellets of crystalline estrone to study their effect upon castrated male chickens (Kleiner et al., 2014).Folkman and Long pioneered implantable formulations, with drug release rates controlled by a polymeric membrane, in the 1960s.Author: Anoop Kumar, Jonathan Pillai
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441594/
Implantable drug delivery systems (DDS) provide a platform for sustained release of therapeutic agents over a period of weeks to months and sometimes years. Such strategies are typically used clinically to increase patient compliance by replacing frequent ...Author: Haoyan Zhou, Christopher Hernandez, Monika Goss, Anna Gawlik, Agata A. Exner
https://www.mdpi.com/2072-666X/3/4/615/pdf
Approaches and Challenges of Engineering Implantable Microelectromechanical Systems (MEMS) Drug Delivery Systems for in Vitro and in Vivo Applications Danny Jian Hang Tng 1, Rui Hu 1, Peiyi Song 1, Indrajit Roy 2 and Ken-Tye Yong 1,* 1 School of Electrical and Electronic Engineering, Nanyang Technological University, Singapore 639798, SingaporeAuthor: Danny Jian Hang Tng, Rui Hu, Peiyi Song, Indrajit Roy, Ken-Tye Yong
http://biomems.usc.edu/publications/2012/2012_BMMD_micropump.pdf
An implantable MEMS micropump system for drug delivery in small animals Heidi Gensler & Roya Sheybani & Po-Ying Li & Ronalee Lo Mann & Ellis Meng Published online: 25 January 2012 # Springer Science+Business Media, LLC 2012 Abstract We present the first implantable drug delivery system for controlled timing and location of dosing in small animals.
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