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https://www.sciencedirect.com/science/article/pii/S0032386108000487
Hydrogels used in drug delivery are usually formed outside of the body and impregnated with drugs before placement of the hydrogel–drug complex in the body. A wide range of cross-linking strategies can be used, including UV photopolymerization and various chemical cross-linking techniques.Author: Todd R. Hoare, Daniel S. Kohane
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384686/
Feb 08, 2019 · In the reservoir delivery system, the hydrogel membrane is coated on a drug-containing core producing capsules, spheres or slabs that have a high drug concentration in the very center of the system to facilitate a constant drug-release rate.Author: Radhika Narayanaswamy, Vladimir P. Torchilin
https://www.sciencedirect.com/science/article/pii/S1359029497801033
Hydrogels and drug delivery Nikolaos A Peppas Recent developments include the use of water-swollen, crosslinked biomedical polymers as carriers for the delivery of drugs, peptides and proteins, as targeting agents for site-specific delivery, or as components for preparation of protein or …Author: Nikolaos A Peppas
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898614/
Hydrogel delivery systems can leverage therapeutically beneficial outcomes of drug delivery and have found clinical use. Hydrogels can provide spatial and temporal control over the release of various therapeutic agents, including small-molecule drugs, macromolecular drugs and cells.Author: Jianyu Li, David J. Mooney
https://www.hindawi.com/journals/ijps/2019/3160732/
Functional Hydrogels and Their Application in Drug Delivery, Biosensors, and Tissue Engineering Hydrogel is a new class of functional polymer materials with a …Author: Ke Wang, Yuting Hao, Yingna Wang, Jinyuan Chen, Lianzhi Mao, Yudi Deng, Junlin Chen, Sijie Yuan, Tia...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781314/
Aug 23, 2019 · Hydrogel synthesis is an essential step in developing new structures with beneficial properties for drug delivery action. The hydrogel structure is defined by the hydration of hydrophilic groups and domains of the polymers involved.Author: Anca Onaciu, Raluca Andrada Munteanu, Alin Iulian Moldovan, Cristian Silviu Moldovan, Ioana Berindan...
https://pubs.acs.org/doi/10.1021/acs.molpharmaceut.9b01020
As an emerging drug carrier, hydrogels have been widely used for tumor drug delivery. A hydrogel drug carrier can cause less severe side effects than systemic chemotherapy and can achieve sustained delivery of a drug at tumor sites.Author: Zhaoyi Sun, Chengjun Song, Chao Wang, Yiqiao Hu, Jinhui Wu
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568318/
Feb 05, 2013 · In another format ( Fig. 2B ), a drug or drug surrogate was tethered to the eight-arm component of a 4 × 8 hydrogel by a releasable linker. Azides of the β-eliminative carbamoyl drug 6, a trace amount of erosion probe, and, when specified, an inert PEG cap were attached to an eight-arm CO-derivatized PEG...Author: Gary W. Ashley, Jeff Henise, Ralph Reid, Daniel V. Santi
https://www.nature.com/articles/natrevmats201671
Oct 18, 2016 · Hydrogel delivery systems can leverage therapeutically beneficial outcomes of drug delivery and have found clinical use. Hydrogels can provide spatial and temporal control over the release of various therapeutic agents, including small-molecule drugs, macromolecular drugs and cells.Author: Jianyu Li, David J. Mooney
https://www.sciencedirect.com/science/article/pii/S0169409X01002034
Hydrogels that are responsive to specific molecules, such as glucose or antigens, can be used as biosensors as well as drug delivery systems. Light-sensitive, pressure-responsive and electro-sensitive hydrogels also have the potential to be used in drug delivery and bioseparation.Author: Yong Qiu, Kinam Park
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