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https://onlinelibrary.wiley.com/doi/abs/10.1002/pat.1677
The drug release behaviors revealed that the grafted beads were both thermo‐ and pH‐sensitive, and the PNIPAAm existed in the pores of the alginate beads acted as the “on–off” gates: the pores of the beads were covered by the stretched PNIPAAm to delay the drug release at 25°C and opened to accelerate the drug release at 37°C because of the shrinking of PNIPAAm molecules.Author: Jun Shi, Xiaopei Liu, Ximeng Sun, Shaokui Cao
https://www.researchgate.net/publication/243797432_Hybrid_alginate_beads_with_thermal-responsive_gates_for_smart_drug_delivery
Compartmentalized biomineralized alginate beads ranging from the micro to the visible scales with thermal- and pH-responsive drug delivery properties have been prepared via a one-step method in ...
https://www.ncbi.nlm.nih.gov/pubmed/20864165
An alginate-based hybrid system for growth factor delivery in the functional repair of large bone defects. Kolambkar YM(1), Dupont KM, Boerckel JD, Huebsch N, Mooney DJ, Hutmacher DW, Guldberg RE.Author: Yash M. Kolambkar, Kenneth M. Dupont, Joel D. Boerckel, Nathaniel Huebsch, David J. Mooney, Dietmar ...
https://www.researchgate.net/publication/5839368_Biomineralized_Polysaccharide_Beads_for_Dual-Stimuli-Responsive_Drug_Delivery
The results suggest that the hybrid alginate beads can be used as “smart” polysaccharide materials for sustained dual-responsive drug delivery. View Show abstract Therapeutic nanomaterials ...
https://www.sciencedirect.com/science/article/pii/S0378517302000546
In this paper the floating drug delivery system employs calcium carbonate (CaCO 3 ) or sodium bicarbonate (NaHCO 3 ) as a gas-forming agent dispersed in an alginate matrix. Alginate is a polysaccharide which contains varying amounts of 1,4′-linked β-d …Author: B. Y. Choi, Hyun Jin Park, S. J. Hwang, J. B. Park
https://link.springer.com/article/10.1007/s42114-019-00082-y
Feb 14, 2019 · In this study, Au nanorods (AuNRs)/mesoporous silica (SiO 2)/hydroxyapatite (HAP) nanovehicles with thermally responsive polymeric cap for remotely controlled drug delivery were prepared.The degradability of the hybrid nanovehicles could be greatly enhanced by introducing pH-responsive HAP into mesoporous SiO 2 shell, which would result in the corrosion of HAP from the hybrid …Author: He Ma, Jun Shi, Xiaoyi Zhu, Zheng Zhang, Jingguo Li, Shaokui Cao
https://www.tandfonline.com/doi/pdf/10.1081/DDC-120003853
controlled-release drug delivery system (12,13). Alginate gel beads seem to be most effective in retarding drugs at higher alginate concentrations (14,15)andwhenthealginatesarerichinguluronic acid(14,16).Theguluronicacidconformationgives ahighdegreeofcoordinationofthecalcium,and therebyformsmorerigidgelsthatarelessproneto
https://www.researchgate.net/publication/268882957_Hierarchically_organization_of_biomineralized_alginate_beads_for_dual_stimuli-responsive_drug_delivery
Hierarchically organization of biomineralized alginate beads for dual stimuli-responsive drug delivery ... the hybrid alginate beads can be used as “smart” polysaccharide materials for ...
https://www.researchgate.net/publication/257193493_Thermal_and_pH_dual_responsive_alginateCaCO3_hybrid_membrane_prepared_under_compressed_CO2
The results suggest that the hybrid alginate beads can be used as “smart” polysaccharide materials for sustained dual-responsive drug delivery.
https://www.researchgate.net/publication/11232706_Alginate_in_Drug_Delivery_Systems
Therefore, ionic crosslinked alginate hydrogels with various structures can be prepared easily. Alginate hydrogels have favourable biological properties, such as biocompatibility, non-antigenicity and biodegradability and are extensively used in wound healing, drug delivery, tissue engineering, cell encapsulation,...
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