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https://www.sciencedirect.com/science/article/pii/S0032386108000487
Significant progress has been made in improving the properties of hydrogels used for drug delivery and expanding the range of drugs and kinetics which can be achieved using a hydrogel-based delivery vehicle. However, several challenges remain to improve …Author: Todd R. Hoare, Daniel S. Kohane
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898614/
The clinical use of drug delivery systems is appreciable 7, with a global market of over $150 US billion in 2013. Hydrogels are a particularly appealing type of drug delivery system, and have been used in many branches of medicine, including cardiology, oncology, immunology, wound …Author: Jianyu Li, David J. Mooney
https://www.researchgate.net/publication/230785490_Hydrogels_as_potential_drug_delivery_systems
Hydrogels, the swellable polymeric materials, have been widely investigated as the carrier for drug delivery systems. These biomaterials have gained attention owing to their peculiar ...
https://www.sciencedirect.com/science/article/pii/S1359644602022559
Drug-release mechanism. Most of the hydrogels are glassy in their dehydrated state, and drug release generally involves simultaneous absorption of water and desorption of drug via a swelling-controlled mechanism .The rate-controlling factor mediating drug delivery is the resistance of the polymer to an increase in volume and change in shape .A glassy hydrogel, on coming into contact with water ...Author: Piyush Gupta, Kavita Vermani, Sanjay Garg
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568318/
Feb 05, 2013 · Hydrogel drug delivery system with predictable and tunable drug release and degradation rates. Gary W. Ashley, Jeff Henise, Ralph Reid, ... Moreover, in addition to s.c. drug delivery, the tunable hydrogels should find utility in other applications, such as regenerative medicine, orthopedic implants, single-shot vaccines, and others.Author: Gary W. Ashley, Jeff Henise, Ralph Reid, Daniel V. Santi
https://www.researchgate.net/publication/285964581_Hydrogels_as_a_drug_delivery_system_and_applications_A_review
Hydrogels as a drug delivery system and applications: A review ... flexible methods of synthesis and tailor able physical properties have made the hydrogels to be used as a drug delivery device to ...
https://www.nature.com/articles/natrevmats201671
Oct 18, 2016 · Hydrogel delivery systems can leverage therapeutically beneficial outcomes of drug delivery and have found clinical use. Hydrogels can provide spatial and …Author: Jianyu Li, David J. Mooney
http://www.orientjchem.org/vol29no3/hydrogels-smart-materials-for-drug-delivery/
The pharmaceutical industry has been developing hydrogel based drug delivery system in an advanced manner by tuning the structure, shape and surface modifications of the biopolymers. The present review highlights the role of hydrogels in drug delivery. It also highlights the use of important polymers and their applications in drug delivery.
https://link.springer.com/chapter/10.1007%2F978-1-59259-427-6_5
Abstract. Hydrogels have played a vital role in the development of controlled-release drug delivery systems. A hydrogel (also called an aquagel) is a three-dimensional (3-D) network of hydrophilic polymers swollen in water (1).The 3-D polymer network of a hydrogel is maintained in the form of elastic solid in the sense that there exists a remembered reference configuration to which the system ...Author: Sung-Joo Hwang, Namjin Baek, Haesun Park, Kinam Park
https://www.hindawi.com/journals/bmri/2017/3564060/
Thermosensitive hydrogels have increasingly received considerable attention for local drug delivery based on many advantages. However, burst release of drugs is becoming a critical challenge when the hydrogels are employed. Microspheres- (MS-) loaded thermosensitive hydrogels were thus fabricated to address this limitation. Employing an orthogonal design, the spray-dried operations of ...Author: Ting-Ting Yang, Yuan-Zheng Cheng, Meng Qin, Yong-Hong Wang, Hong-Li Yu, An-Lin Wang, Wei-Fen Zhang
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