Gene Delivery Using Functional Dendritic Polymers

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Gene delivery using functional dendritic polymers ...

    https://www.researchgate.net/publication/24033942_Gene_delivery_using_functional_dendritic_polymers
    In the present review, we try to bring out the recent trend of studies on functional and biodegradable dendritic polymers as nontoxic and efficient gene delivery vectors.

Gene delivery using functional dendritic polymers.

    https://www.ncbi.nlm.nih.gov/pubmed/19236206
    Gene delivery using functional dendritic polymers. ... This review describes a strategy for the development of multifunctional dendritic polymers for application as gene delivery systems. These polymers can address the low transfection efficiency usually encountered by synthetic non-viral vectors. ... affording complexes that are employed for ...Author: Constantinos M Paleos, Leto-Aikaterini Tziveleka, Zili Sideratou, Dimitris Tsiourvas

Gene delivery using functional dendritic polymers: Expert ...

    https://www.tandfonline.com/doi/abs/10.1517/17425240802607345
    Objective: This review describes a strategy for the development of multifunctional dendritic polymers for application as gene delivery systems.These polymers can address the low transfection efficiency usually encountered by synthetic non-viral vectors. Methods: Employing appropriate, well-characterized and mainly commercially available dendritic polymers, the emphasis is placed primarily on ...Author: Constantinos M Paleos, Leto-Aikaterini Tziveleka, Zili Sideratou, Dimitris Tsiourvas

Molecular Engineering of Dendritic Polymers and Their ...

    https://pubs.acs.org/doi/abs/10.1021/mp060076n
    This review discusses the development of functional and multifunctional dendrimeric and hyperbranched polymers, collectively called dendritic polymers, with the objective of being applied as drug and gene delivery systems. In particular, using as starting materials known and well-characterized basic dendritic polymers, the review deals with the type of structural modifications to which these ...Author: Constantinos M. Paleos, Dimitris Tsiourvas, Zili Sideratou

Design of functional dendritic polymers for application as ...

    https://www.researchgate.net/publication/254391539_Design_of_functional_dendritic_polymers_for_application_as_drug_and_gene_delivery_systems
    Design of functional dendritic polymers for application as drug and gene delivery systems ... in order to be employed as drug and gene delivery systems. In particular, using as starting materials ...

Recent Advances in Targeted Drug Delivery Approaches Using ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519693/
    Jul 01, 2015 · Recent Advances in Targeted Drug Delivery Approaches Using Dendritic Polymers. Jason Bugno, Hao-Jui Hsu, and Seungpyo Hong * ... with a focus on their most recent biomedical advances in targeted drug/gene delivery. Table 1. ... 18 Bioactive functional molecules, ...Author: Jason Bugno, Hao Jui Hsu, Seungpyo Hong

Functional and biodegradable dendritic macromolecules with ...

    https://www.sciencedirect.com/science/article/pii/S0734975013002255
    Functional and biodegradable dendritic macromolecules with controlled architectures as nontoxic and efficient nanoscale gene vectors ... only a few reports described the in vivo gene delivery using dendritic polymers as gene vectors (Alton et al., 2007 ... This review summarizes the functional and biodegradable dendritic macromolecules as ...Author: Kui Luo, Bin He, Yao Wu, Youqing Shen, Zhongwei Gu

Polymer gene delivery: overcoming the obstacles ...

    https://www.sciencedirect.com/science/article/pii/S1359644613002006
    Polymers used for gene delivery vary in molecular weight, structure and molecular composition. Having linear, branched or dendritic structures, these polymers bind DNA electrostatically, reducing the size of the DNA and/or RNA into nano-sized particles (polyplexes) providing protection and …Author: Ahmed Aied, Udo Greiser, Abhay Pandit, Wenxin Wang

Dendritic Polymers and Their Potential Applications

    http://wwwcourses.sens.buffalo.edu/ce435/Dendrimers/Dendrimers
    The "dendritic box" is a fifth generation poly (propylene imine) consisting of 64 functional groups at the periphery. The trapped foreign molecules cannot diffuse out of the box. Only upon prolong heating, the trapped molecules were able to escape. It is possible to use …

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