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https://www.researchgate.net/publication/232077857_Gene_delivery_using_cationic_liposomes
Request PDF Gene delivery using cationic liposomes The development of cationic liposomes for gene delivery has been ongoing for almost 20 years; however, despite extensive efforts to develop a ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066571/
Dec 15, 2010 · However, due to the fact that cationic liposomes can be inactivated in the presence of serum, are unstable upon storage, and exhibit some cytotoxicity both in vitro and in vivo, anionic liposomes have been studied as potential gene delivery vehicles [63–65].Author: Daniel A. Balazs, Wt. Godbey
https://www.researchgate.net/publication/7471375_Cationic_liposomes_for_gene_delivery
Cationic liposomes for gene delivery. ... Aspects related to new trends in the formulation of lipid-based gene delivery systems aiming at overcoming some of their limitations will be covered ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896879/
Nonviral Gene Delivery to Mesenchymal Stem Cells Using Cationic Liposomes for Gene and Cell Therapy. ... The plasmid DNA delivery was optimized using a cationic liposome-based reagent. Transfection efficiencies ranged from ~2% to ~35%, resulting from using a Lipid/DNA ratio of 1.25 with a transgene expression of 7 days. Importantly, the number ...Author: C. Madeira, R. D. Mendes, S. C. Ribeiro, J. S. Boura, M. R. Aires-Barros, C. L. da Silva, J. M. S. C...
https://www.hindawi.com/journals/jdd/2011/326497/
Various anionic liposomes have been characterized for gene delivery in a small number of cell types including CHO cells and primary hippocampal neurons [8, 66, 68, 69].While such investigations are novel, overall knowledge regarding anionic lipofection is as yet limited due to a lack of extensive testing; DNA entrapment in anionic liposomes is still inefficient, and cytotoxicity data remain ...Author: Daniel A. Balazs, Wt. Godbey
https://www.sciencedirect.com/science/article/pii/S0168365906001763
Targeted gene therapy is essential if cancer treatment is to become a reality with this form of therapy. In the past few years, cationic liposomes, discovered 2 decades ago, and at present, the most commonly used class of transfection reagents, have been tested in …Author: Crispin R. Dass, Peter F.M. Choong
https://www.sciencedirect.com/science/article/pii/S181808761300010X
Cationic liposomes have been studied as a means to enhance the stability of nucleic acid therapeutics in the bloodstream and improve their cellular delivery. As nucleic acid therapeutics, siRNA and plasmid DNA have been extensively tested for delivery using cationic liposomes.Author: Gayong Shim, Mi-Gyeong Kim, Joo Yeon Park, Yu-Kyoung Oh
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