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https://journals.lww.com/anesthesia-analgesia/Fulltext/2002/03000/The_Primary_Action_of_Epidural_Fentanyl_After.36.aspx
Our results support the hypothesis that the primary mechanism of analgesia of epidural fentanyl after cesarean delivery is spinal. Our data also show that the total required dose of epidural, but not IV, fentanyl is reduced by very small dose epidural bupivacaine and epinephrine (Group I versus Group IV, P < 0.02 and Group II vs Group III, not significant).
https://anesthesiology.pubs.asahq.org/article.aspx?articleid=2654625
The second and third groups received epidural and combined spinal-epidural analgesia, respectively, both initiated with bupivacaine and fentanyl and maintained with epidural bupivacaine/fentanyl. 7 The mean cumulative fentanyl doses in the epidural and combined spinal-epidural groups were 163 μg and 107 μg, respectively.Author: Amy I. Lee, Robert J. McCarthy, Paloma Toledo, Mary Jane Jones, Nancy White, Cynthia A. Wong
https://anesthesiology.pubs.asahq.org/article.aspx?articleid=1947407
When epidural fentanyl is administered, it either crosses the dura and binds to spinal opioid receptors, is absorbed systemically and binds to supraspinal opioid receptors, or a combination of both. Whether epidural fentanyl in patients in labor produces analgesia predominantly by a primary spinal or supraspinal action is controversial.Author: Robert D'Angelo, J. C. Gerancher, James C. Eisenach, Brenda L. Raphael
https://journals.lww.com/anesthesia-analgesia/Fulltext/1996/09000/Pharmacokinetics_of_Epidural_Fentanyl.69.aspx
The CSF fentanyl concentration after epidural injection reached the maximum by 10-20 min and was maintained steady up to 45 min after injection. However, the plasma fentanyl concentration after an intravenous injection rapidly decreased . We think that a continuous infusion technique is more appropriate than a bolus injection technique in order to obtain the steady plasma concentration in the …
https://www.sciencedaily.com/releases/2017/11/171108124141.htm
Nov 08, 2017 · Including the opioid fentanyl in the solution used to maintain an epidural during childbirth does not appear to affect the success of breastfeeding six weeks after delivery, according to a study.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811299/
Jan 19, 2010 · Effects of Epidural Fentanyl on Speed and Quality of Block for Emergency Cesarean Section in Extending Continuous Epidural Labor Analgesia Using Ropivacaine and Fentanyl Jeong-Yeon Hong , 1 Young Seok Jee , 2 Hyeong Jun Jeong , 1 Young Song , 1 and Hae Keum Kil 1Author: Jeong-Yeon Hong, Young Seok Jee, Hyeong Jun Jeong, Young Song, Hae Keum Kil
https://www.drugs.com/pregnancy/fentanyl.html
Oct 14, 2019 · In women treated acutely with IV or epidural fentanyl during labor, symptoms of neonatal respiratory or neurological depression were no more frequent than would be expected in infants of untreated mothers. Transient neonatal muscular rigidity has been reported in infants whose mothers were treated with IV fentanyl.8.1/10
https://americanpregnancy.org/labor-and-birth/narcotics/
Fentanyl: Fentanyl is a synthetic opiate that provides mild to moderate sedation. The advantages of using Fentanyl include: Begins working quickly (although, usually only lasts 45 minutes) Minimal sedation; Minimal fetal effects; How can Fentanyl affect me and my baby? You and your baby can experience some sedation and/or nausea.
https://americanpregnancy.org/labor-and-birth/epidural/
Oct 13, 2019 · Epidural medications fall into a class of drugs called local anesthetics, such as bupivacaine, chloroprocaine, or lidocaine. They are often delivered in combination with opioids or narcotics such as fentanyl and sufentanil in order to decrease the required dose of local anesthetic.
https://www.drugs.com/dosage/fentanyl.html
Nov 22, 2019 · -Do not begin a patient on a fentanyl transdermal patch as their first opioid..-A small number of patients may require a 48-hour dosing interval; an increase in dose should be evaluated before changing dosing intervals.-For delivery rates in excess of 100 mcg/hour, multiple systems may be used.8.1/10
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