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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546090/
Sep 04, 2018 · Exosomes play a pivotal role in mediating intercellular communications and package delivery. They have recently been discovered to serve as diagnostic biomarkers as well as a possible drug delivery vehicle based on their nanometer size range and capability to …Author: Golam Kibria, Erika K. Ramos, Yong Wan, David R. Gius, Huiping Liu
https://exopharm.com/exosomes-as-drug-delivery-vehicles/
Jan 01, 2017 · Exosomes isolated from cow’s milk, for example, make effective anticancer drug delivery vehicles, boosting the potency of several drugs including paclitaxel (Taxol) and doxorubicin 2. The benefit here stems from the fact the exosomes act as a slow-release reservoir of the drug inside the body, providing a steady stream of the treatment.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951582/
Mar 08, 2016 · 2. Exosomes as drug delivery vehicle. Currently, the most preferred drug delivery systems are liposomes and polymeric nanoparticles. A liposome is a synthetic vesicle with a phospholipid membrane that self-assembles into various sizes and shapes in an aqueous environment46.Author: Dinh Ha, Ningning Yang, Venkatareddy Nadithe
https://cen.acs.org/business/start-ups/Meet-exosome-rising-star-drug/96/i31
Exosomes can deliver therapies into cells that would otherwise be hard to reach. Now they’re positioned to become a widespread tool for drug delivery. Scientists have known about exosomes for decades, but as recently as 2006, only 508, mostly obscure, papers referred to them, according to PubMed.
https://onlinelibrary.wiley.com/doi/abs/10.1002/biot.201900163
The present study aims at creating a new biomanufacturing platform of cancer‐targeted exosomes for drug delivery. Specifically, a scalable, robust, high‐yield, cell line based exosome production process is created in a stirred‐tank bioreactor, and an efficient surface tagging technique is developed to generate monoclonal antibody (mAb)‐exosomes.Author: Yingnan Si, Seulhee Kim, Eric Zhang, Yawen Tang, Renata Jaskula-Sztul, James M Markert, Herbert Chen...
https://www.sciencedirect.com/science/article/pii/S0734975012001474
In conclusion, exosomes represent the most promising candidate for a natural drug delivery vehicle ( Fig. 3 ). It carries many of the desirable attributes of a synthetic liposome vehicle such as the capacity to carry hydrophobic drugs in its bi-lipid membrane and hydrophilic drugs in its aqueous core.Author: Ruenn Chai Lai, Ronne Wee Yeh Yeo, Ronne Wee Yeh Yeo, Kok Hian Tan, Sai Kiang Lim
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