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https://pubs.acs.org/doi/10.1021/acsami.9b13576
Through the photothermal conversion effect of GNRs on the pattern, we further demonstrate on-demand, light-induced delivery of drug molecules to the target cells. We expect that this approach will provide a new way to study single cellular behaviors and enhance molecular delivery to the target cells.Author: Tae Ho Kang, Seungki Lee, Jung A Kwon, Jihwan Song, Inhee Choi
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788045/
Aug 11, 2009 · Molecular Evolution of Adeno-associated Virus for Enhanced Glial Gene Delivery James T Koerber , 1 Ryan Klimczak , 2 Jae-Hyung Jang , 1 Deniz Dalkara , 1 John G Flannery , 2 and David V Schaffer 1 1 Department of Chemical Engineering, Department of Bioengineering, and the Helen Wills Neuroscience Institute, The University of California ...Author: James T Koerber, Ryan Klimczak, Jae-Hyung Jang, Deniz Dalkara, John G Flannery, David V Schaffer
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364662/
Focused Ultrasound-Microbubble Enhanced Antibody Delivery. Although small molecule delivery has some application in AD therapy and diagnostics, we were primarily interested in the delivery of much larger biological molecules, such as antibodies, for AD therapy.Author: Scott Bruce Raymond, Scott Bruce Raymond, Lisa H. Treat, Lisa H. Treat, Jonathan D. Dewey, Nathan Ju...
https://www.sciencedirect.com/science/article/pii/S0144861719304953
Molecular simulation is proposed as a guidance to design an efficient oral drug delivery system. • Oral absorption of doxorubicin was remarkably enhanced by hyaluronic acid grafted fatty glyceride carriers.Author: Yujiao Sun, Haiyang Wu, Wei Dong, Jieyu Zhou, Xin Zhang, Lijuan Liu, Xiaofei Zhang, Hongbo Cheng, Ji...
https://pubs.acs.org/doi/10.1021/jacs.0c00188
Mitochondria play a key role in oncogenesis and constitute one of the most important targets for cancer treatments. Although the most effective way to deliver drugs to mitochondria is by covalently linking them to a lipophilic cation, the in vivo delivery of free drugs still constitutes a critical bottleneck. Herein, we report the design of a mitochondria-targeted metal–organic framework ...Author: Salame Haddad, Isabel Abanades Lazaro, Marcus Fantham, Ajay Mishra, Joaquin Silvestre-Albero, Johann...
https://advances.sciencemag.org/content/6/8/eaay6812.full
Feb 01, 2020 · Duchenne muscular dystrophy (DMD) is a lethal neuromuscular disease caused by mutations in the dystrophin gene ( DMD ). Previously, we applied CRISPR-Cas9–mediated “single-cut” genome editing to correct diverse genetic mutations in animal models of DMD. However, high doses of adeno-associated virus (AAV) are required for efficient in vivo genome editing, posing challenges for …Author: Yu Zhang, Hui Li, Yi-Li Min, Efrain Sanchez-Ortiz, Jian Huang, Alex A. Mireault, John M. Shelton, Ji...
https://advances.sciencemag.org/content/5/10/eaaw6870.full
Oct 01, 2019 · Erythrocytes or red blood cells (RBCs) represent a promising cell-mediated drug delivery platform due to their inherent biocompatibility. Here, we developed an antigen delivery system based on the nanoerythrosomes derived from RBCs, inspired by the splenic antigen-presenting cell targeting capacity of senescent RBCs. Tumor antigens were loaded onto the nanoerythrosomes by fusing …Author: Xiao Han, Shufang Shen, Qin Fan, Guojun Chen, Edikan Archibong, Gianpietro Dotti, Zhuang Liu, Zhen G...
https://www.powershow.com/view2b/3f455b-Nzk1Y/Enhanced_molecular_delivery_powerpoint_ppt_presentation
Enhanced molecular delivery anti-aging program What is LifePak Nano? A comprehensive nutritional wellness program delivering optimal amounts of essential and semi ... – A free PowerPoint PPT presentation (displayed as a Flash slide show) on PowerShow.com - id: 3f455b-Nzk1Y
https://www.nature.com/articles/s41598-018-22571-8
Mar 07, 2018 · Image-Guided Focused-Ultrasound CNS Molecular Delivery: An Implementation via Dynamic Contrast-Enhanced Magnetic-Resonance Imaging Skip to …Author: Wen-Yen Chai, Wen-Yen Chai, Po-Chun Chu, Chih-Hung Tsai, Chung-Yin Lin, Hung-Wei Yang, Hsin-Yi Lai, ...
https://www.nuskin.com/global/library/pdf/pxscan_lpnano.pdf
Enhanced molecular delivery anti-aging program. What is LifePak Nano? A comprehensive nutritional wellness program delivering optimal amounts of essential and semiessential and semi--essential micro essential micro--and macronutrients typically lacking in diets, for the support of all body
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