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https://www.sciencedirect.com/science/article/pii/S001448000800141X
Indeed, reduced dosage is a critical factor for limiting systemic toxicity. Clinical trials are planned for testing this method of drug delivery. Dendrimers. In early studies, dendrimer-based drug delivery systems focused on encapsulating drugs. However, it was difficult …Author: Rajesh Singh, James W. Lillard, James W. Lillard
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249419/
Targeted drug delivery. The development of nanoparticle delivery systems for targeted drug delivery has been recently reviewed (Moghimi et al., 2001). Targeted delivery can be actively or passively achieved.Author: Rajesh Singh, James W. Lillard, James W. Lillard
https://www.sciencedirect.com/science/article/abs/pii/S001448000800141X
Nanotechnology could be defined as the technology that has allowed for the control, manipulation, study, and manufacture of structures and devices in …Author: Rajesh Singh, James W. Lillard, James W. Lillard
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527668/
The non restricted (cyto)toxicity of chemotherapeutics thus limits the full use of their therapeutic potential. Local drug delivery or drug targeting results in increased local drug concentrations and provides strategies for more specific therapy. Nanoparticles have specific particles as …Author: Wim H De Jong, Paul Ja Borm
https://www.hindawi.com/journals/jnm/2016/1087250/
Nanoparticles have shown promise as both drug delivery vehicles and direct antitumor systems, but they must be properly designed in order to maximize efficacy. Computational modeling is often used both to design new nanoparticles and to better understand existing ones. Modeled processes include the release of drugs at the tumor site and the physical interaction between the nanoparticle and ...Author: Xiaojiao Yu, Ian Trase, Muqing Ren, Kayla Duval, Xing Guo, Zi Chen
https://www.researchgate.net/publication/23967881_Nanoparticle-based_targeted_drug_delivery
Nanoparticle are highly being studied in drug development process as their size is very small and thus help in efficient targeted drug delivery especially of those drugs which are not effectively ...
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