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https://www.ncbi.nlm.nih.gov/pubmed/14759812
Flexible alteration of virus surface properties would be beneficial for enhanced and targeted gene delivery. A useful approach could be based on a high-affinity receptor-ligand pair, such as avidin and biotin. In this study, we have constructed an avidin-displaying baculovirus, Baavi.Author: Jani K Räty, Kari J Airenne, Ari T Marttila, Varpu Marjomäki, Vesa P Hytönen, Pauliina Lehtolainen, ...
https://www.sciencedirect.com/science/article/pii/S1525001603003654
Flexible alteration of virus surface properties would be beneficial for enhanced and targeted gene delivery. A useful approach could be based on a high-affinity receptor–ligand pair, such as avidin and biotin. In this study, we have constructed an avidin-displaying baculovirus, Baavi.Author: Jani K Räty, Kari J Airenne, Ari T Marttila, Varpu Marjomäki, Vesa P Hytönen, Pauliina Lehtolainen, ...
https://www.cell.com/molecular-therapy-family/molecular-therapy/fulltext/S1525-0016(03)00365-4
Flexible alteration of virus surface properties would be beneficial for enhanced and targeted gene delivery. A useful approach could be based on a high-affinity receptor–ligand pair, such as avidin and biotin. In this study, we have constructed an avidin-displaying baculovirus, Baavi. Avidin display was expected to enhance cell transduction due to the high positive charge of avidin in ...Author: Jani K Räty, Kari J Airenne, Ari T Marttila, Varpu Marjomäki, Vesa P Hytönen, Pauliina Lehtolainen, ...
https://www.researchgate.net/publication/8888592_Enhanced_Gene_Delivery_by_Avidin-Displaying_Baculovirus
Flexible alteration of virus surface properties would be beneficial for enhanced and targeted gene delivery. A useful approach could be based on a high-affinity receptor-ligand pair, such as ...
https://www.researchgate.net/profile/Jani_Raety/publication/42426238_Baculovirus_surface_modifications_for_enhanced_gene_delivery_and_biodistribution_imaging_Bakulovirusten_pintaproteiinien_muokkaaminen_geeniterapian_tehostamista_ja_kulkeutumisen_kuvantamista_varten/links/0fcfd508a6fe83c404000000.pdf?origin=publication_detail
Baculovirus Surface Modifications for Enhanced Gene Delivery and Biodistribution Imaging Doctoral dissertation To be presented by permission of the Faculty of Natural and Environmental Sciences of ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1316037/
Jul 31, 2005 · Knowledge of the interaction of baculovirus with mammalian cells is essential for the development of baculovirus-based gene delivery vectors. So far, baculovirus vectors have been shown to transduce various dividing and nondividing mammalian cell lines in ... Enhanced gene delivery by avidin-displaying baculovirus. Mol. Ther. 9:282-291 ...Author: Heli Matilainen, Johanna Rinne, Leona Gilbert, Varpu Marjomäki, Hilkka Reunanen, Christian Oker-Blom
https://www.sciencedirect.com/science/article/pii/S0065352706680032
The efficiency of gene delivery in vivo has also been explored using VSV‐G–pseudotyped baculovirus vectors. The modified virus enhanced transgene delivery by five‐ to tenfold when mouse myoblasts and myotubes were transduced in vitro (Pieroni et al., 2001).Author: Anna R. Mäkelä, Christian Oker‐Blom
https://www.nature.com/articles/3302934
Apr 05, 2007 · We have previously reported the construction of a novel avidin-displaying baculovirus (Baavi) with enhanced transduction efficiency in vitro 16 and showed it to be suitable for viral particle ...Author: J K Räty, T Liimatainen, T Huhtala, M U Kaikkonen, K J Airenne, J M Hakumäki, A Närvänen, S Ylä-Hert...
https://www.nature.com/articles/3302657
Nov 03, 2005 · Raty JK, Airenne KJ, Marttila AT, Marjomaki V, Hytonen VP, Lehtolainen P et al. Enhanced gene delivery by avidin-displaying baculovirus. Mol Ther 2004; 9 : 282–291. CASAuthor: Minna U. Kaikkonen, Jani K. Raty, Kari J. Airenne, Thomas Wirth, Tommi Heikura, Seppo Yla-Herttuala
http://www.eurekaselect.com/79314
An interesting new exploitation for avidin-biotin techniques is the utilization of this strong affinity in gene therapy, to target and enhance gene delivery to the appropriate target cells and tissues. In this communication, we review novel avidin fusion proteins that have been developed for enhanced gene delivery and drug targeting purposes.Author: Olli H. Laitinen, Kari J. Airenne, Jani K. Raty, Thomas Wirth, Seppo Yla-Herttuala
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